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2-Aminoimidazoles Inhibit Mycobacterium abscessus Biofilms in a Zinc-Dependent Manner
Biofilm growth is thought to be a significant obstacle to the successful treatment of Mycobacterium abscessus infections. A search for agents capable of inhibiting M. abscessus biofilms led to our interest in 2-aminoimidazoles and related scaffolds, which have proven to display antibiofilm propertie...
Autores principales: | Belardinelli, Juan M., Li, Wei, Martin, Kevin H., Zeiler, Michael J., Lian, Elena, Avanzi, Charlotte, Wiersma, Crystal J., Nguyen, Tuan Vu, Angala, Bhanupriya, de Moura, Vinicius C. N., Jones, Victoria, Borlee, Bradley R., Melander, Christian, Jackson, Mary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951752/ https://www.ncbi.nlm.nih.gov/pubmed/35328372 http://dx.doi.org/10.3390/ijms23062950 |
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