Fabrication of Multiple Parallel Microchannels in a Single Microgroove via the Heating Assisted MIMIC Technique

For the first time, multiple parallel microchannels in a single microgroove have been fabricated by the heating-assisted micromolding in capillaries technique (HAMIMIC). Microchannel development, cross-sectional shape, and length were all explored in depth. The factors affecting the cross-sectional...

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Autores principales: Zhang, Dengying, Xing, Wenqiang, Li, Weiren, Liu, Shengming, Dong, Yanli, Zhang, Lichun, Zhao, Fengzhou, Wang, Jun, Xu, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952235/
https://www.ncbi.nlm.nih.gov/pubmed/35334655
http://dx.doi.org/10.3390/mi13030364
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author Zhang, Dengying
Xing, Wenqiang
Li, Weiren
Liu, Shengming
Dong, Yanli
Zhang, Lichun
Zhao, Fengzhou
Wang, Jun
Xu, Zheng
author_facet Zhang, Dengying
Xing, Wenqiang
Li, Weiren
Liu, Shengming
Dong, Yanli
Zhang, Lichun
Zhao, Fengzhou
Wang, Jun
Xu, Zheng
author_sort Zhang, Dengying
collection PubMed
description For the first time, multiple parallel microchannels in a single microgroove have been fabricated by the heating-assisted micromolding in capillaries technique (HAMIMIC). Microchannel development, cross-sectional shape, and length were all explored in depth. The factors affecting the cross-sectional shape and length of the double-microchannel were also discussed. Finally, a special-shaped PDMS guiding mold was designed to control the cross-sectional shape and length of multiple parallel microchannels for controlled growth. The HAMIMIC technique provides a low-cost, straightforward, and repeatable way to create multiple parallel microchannels in a single microgroove, and will promote the progress of bifurcated vessels and thrombus vessels preparation technology.
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spelling pubmed-89522352022-03-26 Fabrication of Multiple Parallel Microchannels in a Single Microgroove via the Heating Assisted MIMIC Technique Zhang, Dengying Xing, Wenqiang Li, Weiren Liu, Shengming Dong, Yanli Zhang, Lichun Zhao, Fengzhou Wang, Jun Xu, Zheng Micromachines (Basel) Article For the first time, multiple parallel microchannels in a single microgroove have been fabricated by the heating-assisted micromolding in capillaries technique (HAMIMIC). Microchannel development, cross-sectional shape, and length were all explored in depth. The factors affecting the cross-sectional shape and length of the double-microchannel were also discussed. Finally, a special-shaped PDMS guiding mold was designed to control the cross-sectional shape and length of multiple parallel microchannels for controlled growth. The HAMIMIC technique provides a low-cost, straightforward, and repeatable way to create multiple parallel microchannels in a single microgroove, and will promote the progress of bifurcated vessels and thrombus vessels preparation technology. MDPI 2022-02-25 /pmc/articles/PMC8952235/ /pubmed/35334655 http://dx.doi.org/10.3390/mi13030364 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhang, Dengying
Xing, Wenqiang
Li, Weiren
Liu, Shengming
Dong, Yanli
Zhang, Lichun
Zhao, Fengzhou
Wang, Jun
Xu, Zheng
Fabrication of Multiple Parallel Microchannels in a Single Microgroove via the Heating Assisted MIMIC Technique
title Fabrication of Multiple Parallel Microchannels in a Single Microgroove via the Heating Assisted MIMIC Technique
title_full Fabrication of Multiple Parallel Microchannels in a Single Microgroove via the Heating Assisted MIMIC Technique
title_fullStr Fabrication of Multiple Parallel Microchannels in a Single Microgroove via the Heating Assisted MIMIC Technique
title_full_unstemmed Fabrication of Multiple Parallel Microchannels in a Single Microgroove via the Heating Assisted MIMIC Technique
title_short Fabrication of Multiple Parallel Microchannels in a Single Microgroove via the Heating Assisted MIMIC Technique
title_sort fabrication of multiple parallel microchannels in a single microgroove via the heating assisted mimic technique
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952235/
https://www.ncbi.nlm.nih.gov/pubmed/35334655
http://dx.doi.org/10.3390/mi13030364
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