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Identification of critical residues of O-antigen-modifying O-acetyltransferase B (OacB) of Shigella flexneri

BACKGROUND: Shigellosis is an acute gastrointestinal disease caused primarily by the bacterium Shigella flexneri. Upon ingestion, S. flexneri initiates a serotype-specific immune response that targets the O-antigen of the pathogen’s lipopolysaccharide. O-antigen subunits are modified by the addition...

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Detalles Bibliográficos
Autores principales: Rajput, Munazza I., Verma, Naresh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952252/
https://www.ncbi.nlm.nih.gov/pubmed/35331134
http://dx.doi.org/10.1186/s12860-022-00415-8