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Targeting DNA Damage Response and Immune Checkpoint for Anticancer Therapy
Deficiency in DNA damage response (DDR) genes leads to impaired DNA repair functions that will induce genomic instability and facilitate cancer development. However, alterations of DDR genes can serve as biomarkers for the selection of suitable patients to receive specific therapeutics, such as immu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952261/ https://www.ncbi.nlm.nih.gov/pubmed/35328658 http://dx.doi.org/10.3390/ijms23063238 |