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Synthesis of Multiple Bispecific Antibody Formats with Only One Single Enzyme Based on Enhanced Trypsiligase †

Bispecific antibodies (bsAbs) were first developed in the 1960s and are now emerging as a leading class of immunotherapies for cancer treatment with the potential to further improve clinical efficacy and safety. Many different formats of bsAbs have been established in the last few years, mainly gene...

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Detalles Bibliográficos
Autores principales: Voigt, Johanna, Meyer, Christoph, Bordusa, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952323/
https://www.ncbi.nlm.nih.gov/pubmed/35328563
http://dx.doi.org/10.3390/ijms23063144