Synthesis, In Silico, and Biological Evaluation of a Borinic Tryptophan-Derivative That Induces Melatonin-like Amelioration of Cognitive Deficit in Male Rat

Preclinical and clinical evidence supports melatonin and its analogues as potential treatment for diseases involving cognitive deficit such as Alzheimer’s disease. In this work, we evaluated by in silico studies a set of boron-containing melatonin analogues on MT1 and MT2 receptors. Then, we synthes...

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Detalles Bibliográficos
Autores principales: Barrón-González, Mónica, Rosales-Hernández, Martha C., Abad-García, Antonio, Ocampo-Néstor, Ana L., Santiago-Quintana, José M., Pérez-Capistran, Teresa, Trujillo-Ferrara, José G., Padilla-Martínez, Itzia I., Farfán-García, Eunice D., Soriano-Ursúa, Marvin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952423/
https://www.ncbi.nlm.nih.gov/pubmed/35328650
http://dx.doi.org/10.3390/ijms23063229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952423/
https://www.ncbi.nlm.nih.gov/pubmed/35328650
http://dx.doi.org/10.3390/ijms23063229

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