Cargando…

HCV Elimination in Central Europe with Particular Emphasis on Microelimination in Prisons

In 2016, the WHO announced a plan to eliminate viral hepatitis as a public health threat by 2030. In this narrative review, experts from Bulgaria, Croatia, the Czech Republic, Hungary, Latvia, Lithuania, Poland and Slovakia assessed the feasibility of achieving the WHO 2030 target for HCV infections...

Descripción completa

Detalles Bibliográficos
Autores principales: Flisiak, Robert, Zarębska-Michaluk, Dorota, Ciupkeviciene, Egle, Drazilova, Sylvia, Frankova, Sona, Grgurevic, Ivica, Hunyady, Bela, Jarcuska, Peter, Kupčinskas, Limas, Makara, Michael, Saulite-Vanaga, Gunita, Simonova, Marieta, Sperl, Jan, Tolmane, Ieva, Vince, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952509/
https://www.ncbi.nlm.nih.gov/pubmed/35336889
http://dx.doi.org/10.3390/v14030482
_version_ 1784675627488509952
author Flisiak, Robert
Zarębska-Michaluk, Dorota
Ciupkeviciene, Egle
Drazilova, Sylvia
Frankova, Sona
Grgurevic, Ivica
Hunyady, Bela
Jarcuska, Peter
Kupčinskas, Limas
Makara, Michael
Saulite-Vanaga, Gunita
Simonova, Marieta
Sperl, Jan
Tolmane, Ieva
Vince, Adriana
author_facet Flisiak, Robert
Zarębska-Michaluk, Dorota
Ciupkeviciene, Egle
Drazilova, Sylvia
Frankova, Sona
Grgurevic, Ivica
Hunyady, Bela
Jarcuska, Peter
Kupčinskas, Limas
Makara, Michael
Saulite-Vanaga, Gunita
Simonova, Marieta
Sperl, Jan
Tolmane, Ieva
Vince, Adriana
author_sort Flisiak, Robert
collection PubMed
description In 2016, the WHO announced a plan to eliminate viral hepatitis as a public health threat by 2030. In this narrative review, experts from Bulgaria, Croatia, the Czech Republic, Hungary, Latvia, Lithuania, Poland and Slovakia assessed the feasibility of achieving the WHO 2030 target for HCV infections in Central Europe. They focused mainly on HCV micro-elimination in prisons, where the highest incidence of HCV infections is usually observed, and the impact of the COVID-19 pandemic on the detection and treatment of HCV infections. According to the presented estimates, almost 400,000 people remain infected with HCV in the analyzed countries. Interferon-free therapies are available ad libitum, but the number of patients treated annually in the last two years has halved compared to 2017–2019, mainly due to the COVID-19 pandemic. None of the countries analyzed had implemented a national HCV screening program or a prison screening program. The main reason is a lack of will at governmental and prison levels. None of the countries analyzed see any chance of meeting the WHO targets for removing viral hepatitis from the public threat list by 2030, unless barriers such as a lack of political will and a lack of screening programs are removed quickly.
format Online
Article
Text
id pubmed-8952509
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-89525092022-03-26 HCV Elimination in Central Europe with Particular Emphasis on Microelimination in Prisons Flisiak, Robert Zarębska-Michaluk, Dorota Ciupkeviciene, Egle Drazilova, Sylvia Frankova, Sona Grgurevic, Ivica Hunyady, Bela Jarcuska, Peter Kupčinskas, Limas Makara, Michael Saulite-Vanaga, Gunita Simonova, Marieta Sperl, Jan Tolmane, Ieva Vince, Adriana Viruses Review In 2016, the WHO announced a plan to eliminate viral hepatitis as a public health threat by 2030. In this narrative review, experts from Bulgaria, Croatia, the Czech Republic, Hungary, Latvia, Lithuania, Poland and Slovakia assessed the feasibility of achieving the WHO 2030 target for HCV infections in Central Europe. They focused mainly on HCV micro-elimination in prisons, where the highest incidence of HCV infections is usually observed, and the impact of the COVID-19 pandemic on the detection and treatment of HCV infections. According to the presented estimates, almost 400,000 people remain infected with HCV in the analyzed countries. Interferon-free therapies are available ad libitum, but the number of patients treated annually in the last two years has halved compared to 2017–2019, mainly due to the COVID-19 pandemic. None of the countries analyzed had implemented a national HCV screening program or a prison screening program. The main reason is a lack of will at governmental and prison levels. None of the countries analyzed see any chance of meeting the WHO targets for removing viral hepatitis from the public threat list by 2030, unless barriers such as a lack of political will and a lack of screening programs are removed quickly. MDPI 2022-02-26 /pmc/articles/PMC8952509/ /pubmed/35336889 http://dx.doi.org/10.3390/v14030482 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Flisiak, Robert
Zarębska-Michaluk, Dorota
Ciupkeviciene, Egle
Drazilova, Sylvia
Frankova, Sona
Grgurevic, Ivica
Hunyady, Bela
Jarcuska, Peter
Kupčinskas, Limas
Makara, Michael
Saulite-Vanaga, Gunita
Simonova, Marieta
Sperl, Jan
Tolmane, Ieva
Vince, Adriana
HCV Elimination in Central Europe with Particular Emphasis on Microelimination in Prisons
title HCV Elimination in Central Europe with Particular Emphasis on Microelimination in Prisons
title_full HCV Elimination in Central Europe with Particular Emphasis on Microelimination in Prisons
title_fullStr HCV Elimination in Central Europe with Particular Emphasis on Microelimination in Prisons
title_full_unstemmed HCV Elimination in Central Europe with Particular Emphasis on Microelimination in Prisons
title_short HCV Elimination in Central Europe with Particular Emphasis on Microelimination in Prisons
title_sort hcv elimination in central europe with particular emphasis on microelimination in prisons
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952509/
https://www.ncbi.nlm.nih.gov/pubmed/35336889
http://dx.doi.org/10.3390/v14030482
work_keys_str_mv AT flisiakrobert hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT zarebskamichalukdorota hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT ciupkevicieneegle hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT drazilovasylvia hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT frankovasona hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT grgurevicivica hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT hunyadybela hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT jarcuskapeter hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT kupcinskaslimas hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT makaramichael hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT saulitevanagagunita hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT simonovamarieta hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT sperljan hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT tolmaneieva hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons
AT vinceadriana hcveliminationincentraleuropewithparticularemphasisonmicroeliminationinprisons