Transient astrocytic mGluR5 expression drives synaptic plasticity and subsequent chronic pain in mice

Activation of astrocytes has a profound effect on brain plasticity and is critical for the pathophysiology of several neurological disorders including neuropathic pain. Here, we show that metabotropic glutamate receptor 5 (mGluR5), which reemerges in astrocytes in a restricted time frame, is essenti...

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Detalles Bibliográficos
Autores principales: Danjo, Yosuke, Shigetomi, Eiji, Hirayama, Yukiho J., Kobayashi, Kenji, Ishikawa, Tatsuya, Fukazawa, Yugo, Shibata, Keisuke, Takanashi, Kenta, Parajuli, Bijay, Shinozaki, Youichi, Kim, Sun Kwang, Nabekura, Junichi, Koizumi, Schuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952801/
https://www.ncbi.nlm.nih.gov/pubmed/35319723
http://dx.doi.org/10.1084/jem.20210989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952801/
https://www.ncbi.nlm.nih.gov/pubmed/35319723
http://dx.doi.org/10.1084/jem.20210989

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