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Transient astrocytic mGluR5 expression drives synaptic plasticity and subsequent chronic pain in mice
Activation of astrocytes has a profound effect on brain plasticity and is critical for the pathophysiology of several neurological disorders including neuropathic pain. Here, we show that metabotropic glutamate receptor 5 (mGluR5), which reemerges in astrocytes in a restricted time frame, is essenti...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952801/ https://www.ncbi.nlm.nih.gov/pubmed/35319723 http://dx.doi.org/10.1084/jem.20210989 |