Novel Prenylated Indole Alkaloids with Neuroprotection on SH-SY5Y Cells against Oxidative Stress Targeting Keap1–Nrf2

Oxidative stress has been implicated in the etiology of Parkinson’s disease (PD). Molecules non-covalently binding to the Keap1–Nrf2 complex could be a promising therapeutic approach for PD. Herein, two novel prenylated indole alkaloids asperpenazine (1), and asperpendoline (2) with a scarce skeleto...

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Detalles Bibliográficos
Autores principales: Xiao, Xueyang, Tong, Zhou, Zhang, Yuexing, Zhou, Hui, Luo, Mengying, Hu, Tianhui, Hu, Ping, Kong, Luqi, Liu, Zeqin, Yu, Chan, Huang, Zhiyong, Hu, Linzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952805/
https://www.ncbi.nlm.nih.gov/pubmed/35323490
http://dx.doi.org/10.3390/md20030191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952805/
https://www.ncbi.nlm.nih.gov/pubmed/35323490
http://dx.doi.org/10.3390/md20030191

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