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Successive Pandemic Waves with Different Virulent Strains and the Effects of Vaccination for SARS-CoV-2
One hundred years after the flu pandemic of 1918, the world faces an outbreak of a new severe acute respiratory syndrome, caused by a novel coronavirus. With a high transmissibility, the pandemic has spread worldwide, creating a scenario of devastation in many countries. By the middle of 2021, about...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952817/ https://www.ncbi.nlm.nih.gov/pubmed/35334975 http://dx.doi.org/10.3390/vaccines10030343 |
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author | Castro e Silva, Alcides Bernardes, Américo Tristão Barbosa, Eduardo Augusto Gonçalves Chagas, Igor Aparecido Santana das Dáttilo, Wesley Reis, Alexandre Barbosa Ribeiro, Sérvio Pontes |
author_facet | Castro e Silva, Alcides Bernardes, Américo Tristão Barbosa, Eduardo Augusto Gonçalves Chagas, Igor Aparecido Santana das Dáttilo, Wesley Reis, Alexandre Barbosa Ribeiro, Sérvio Pontes |
author_sort | Castro e Silva, Alcides |
collection | PubMed |
description | One hundred years after the flu pandemic of 1918, the world faces an outbreak of a new severe acute respiratory syndrome, caused by a novel coronavirus. With a high transmissibility, the pandemic has spread worldwide, creating a scenario of devastation in many countries. By the middle of 2021, about 3% of the world population had been infected and more than 4 million people had died. Different from the H1N1 pandemic, which had a deadly wave and ceased, the new disease is maintained by successive waves, mainly produced by new virus variants and the small number of vaccinated people. In the present work, we create a version of the SIR model using the spatial localization of persons, their movements, and considering social isolation probabilities. We discuss the effects of virus variants, and the role of vaccination rate in the pandemic dynamics. We show that, unless a global vaccination is implemented, we will have continuous waves of infections. |
format | Online Article Text |
id | pubmed-8952817 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89528172022-03-26 Successive Pandemic Waves with Different Virulent Strains and the Effects of Vaccination for SARS-CoV-2 Castro e Silva, Alcides Bernardes, Américo Tristão Barbosa, Eduardo Augusto Gonçalves Chagas, Igor Aparecido Santana das Dáttilo, Wesley Reis, Alexandre Barbosa Ribeiro, Sérvio Pontes Vaccines (Basel) Article One hundred years after the flu pandemic of 1918, the world faces an outbreak of a new severe acute respiratory syndrome, caused by a novel coronavirus. With a high transmissibility, the pandemic has spread worldwide, creating a scenario of devastation in many countries. By the middle of 2021, about 3% of the world population had been infected and more than 4 million people had died. Different from the H1N1 pandemic, which had a deadly wave and ceased, the new disease is maintained by successive waves, mainly produced by new virus variants and the small number of vaccinated people. In the present work, we create a version of the SIR model using the spatial localization of persons, their movements, and considering social isolation probabilities. We discuss the effects of virus variants, and the role of vaccination rate in the pandemic dynamics. We show that, unless a global vaccination is implemented, we will have continuous waves of infections. MDPI 2022-02-22 /pmc/articles/PMC8952817/ /pubmed/35334975 http://dx.doi.org/10.3390/vaccines10030343 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Castro e Silva, Alcides Bernardes, Américo Tristão Barbosa, Eduardo Augusto Gonçalves Chagas, Igor Aparecido Santana das Dáttilo, Wesley Reis, Alexandre Barbosa Ribeiro, Sérvio Pontes Successive Pandemic Waves with Different Virulent Strains and the Effects of Vaccination for SARS-CoV-2 |
title | Successive Pandemic Waves with Different Virulent Strains and the Effects of Vaccination for SARS-CoV-2 |
title_full | Successive Pandemic Waves with Different Virulent Strains and the Effects of Vaccination for SARS-CoV-2 |
title_fullStr | Successive Pandemic Waves with Different Virulent Strains and the Effects of Vaccination for SARS-CoV-2 |
title_full_unstemmed | Successive Pandemic Waves with Different Virulent Strains and the Effects of Vaccination for SARS-CoV-2 |
title_short | Successive Pandemic Waves with Different Virulent Strains and the Effects of Vaccination for SARS-CoV-2 |
title_sort | successive pandemic waves with different virulent strains and the effects of vaccination for sars-cov-2 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8952817/ https://www.ncbi.nlm.nih.gov/pubmed/35334975 http://dx.doi.org/10.3390/vaccines10030343 |
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