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Repurposing Avasimibe to Inhibit Bacterial Glycosyltransferases

We are interested in identifying and characterizing small molecule inhibitors of bacterial virulence factors for their potential use as anti-virulence inhibitors. We identified from high-throughput screening assays a potential activity for avasimibe, a previously characterized acyl-coenzyme A: chole...

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Detalles Bibliográficos
Autores principales: Hasan, Md Kamrul, El Qaidi, Samir, McDonald, Peter, Roy, Anuradha, Hardwidge, Philip R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953086/
https://www.ncbi.nlm.nih.gov/pubmed/35335693
http://dx.doi.org/10.3390/pathogens11030370