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A New Fungal Triterpene from the Fungus Aspergillus flavus Stimulates Glucose Uptake without Fat Accumulation

Through activity-guided fractionation, a new triterpene (asperflagin, 1) was isolated as a PPAR-γ agonist from the jellyfish-derived fungus Aspergillus flavus. Asperflagin displayed selective and moderate transactivation effects on PPAR-γ in Ac2F rat liver cells. Based on further biological evaluati...

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Detalles Bibliográficos
Autores principales: Li, Dan-dan, Wang, Ying, Kim, Eun La, Hong, Jongki, Jung, Jee H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953101/
https://www.ncbi.nlm.nih.gov/pubmed/35323502
http://dx.doi.org/10.3390/md20030203