A High Body Mass Index and the Vacuum Phenomenon Upregulate Pain-Related Molecules in Human Degenerated Intervertebral Discs

Animal studies suggest that pain-related-molecule upregulation in degenerated intervertebral discs (IVDs) potentially leads to low back pain (LBP). We hypothesized that IVD mechanical stress and axial loading contribute to discogenic LBP’s pathomechanism. This study aimed to elucidate the relationsh...

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Detalles Bibliográficos
Autores principales: Miyagi, Masayuki, Uchida, Kentaro, Inoue, Sho, Takano, Shotaro, Nakawaki, Mitsufumi, Kawakubo, Ayumu, Sekiguchi, Hiroyuki, Nakazawa, Toshiyuki, Imura, Takayuki, Saito, Wataru, Shirasawa, Eiki, Kuroda, Akiyoshi, Ikeda, Shinsuke, Yokozeki, Yuji, Mimura, Yusuke, Akazawa, Tsutomu, Takaso, Masashi, Inoue, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953228/
https://www.ncbi.nlm.nih.gov/pubmed/35328395
http://dx.doi.org/10.3390/ijms23062973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953228/
https://www.ncbi.nlm.nih.gov/pubmed/35328395
http://dx.doi.org/10.3390/ijms23062973

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