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Antioxidant and Anti-Inflammatory Effects of Coenzyme Q10 Supplementation on Infectious Diseases
With the appearance of new viruses and infectious diseases (ID) such as COVID-19 in 2019, as well as the lack of specific pharmacological tools for the management of patients with severe complications or comorbidities, it is important to search for adjuvant treatments that help improve the prognosis...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953254/ https://www.ncbi.nlm.nih.gov/pubmed/35326965 http://dx.doi.org/10.3390/healthcare10030487 |
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author | Sifuentes-Franco, Sonia Sánchez-Macías, Dellaneira Carolina Carrillo-Ibarra, Sandra Rivera-Valdés, Juan José Zuñiga, Laura Y. Sánchez-López, Virginia Aleyda |
author_facet | Sifuentes-Franco, Sonia Sánchez-Macías, Dellaneira Carolina Carrillo-Ibarra, Sandra Rivera-Valdés, Juan José Zuñiga, Laura Y. Sánchez-López, Virginia Aleyda |
author_sort | Sifuentes-Franco, Sonia |
collection | PubMed |
description | With the appearance of new viruses and infectious diseases (ID) such as COVID-19 in 2019, as well as the lack of specific pharmacological tools for the management of patients with severe complications or comorbidities, it is important to search for adjuvant treatments that help improve the prognosis of infectious disease patients. It is also important that these treatments limit the oxidative and hyperinflammatory damage caused as a response to pathogenic agents, since, in some cases, an inflammatory syndrome may develop that worsens the patient’s prognosis. The potential benefits of complementary nutrients and dietary interventions in the treatment of pathological processes in which oxidative stress and inflammation play a fundamental role have been widely evaluated. Coenzyme Q10 (CoQ10) is a supplement that has been shown to protect cells and be effective in cardiovascular diseases and obesity. Additionally, some studies have proposed it as a possible adjuvant treatment in viral infections. Preclinical and clinical studies have shown that CoQ10 has anti-inflammatory and antioxidant effects, and effects on mitochondrial dysfunction, which have been linked to the inflammatory response. |
format | Online Article Text |
id | pubmed-8953254 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89532542022-03-26 Antioxidant and Anti-Inflammatory Effects of Coenzyme Q10 Supplementation on Infectious Diseases Sifuentes-Franco, Sonia Sánchez-Macías, Dellaneira Carolina Carrillo-Ibarra, Sandra Rivera-Valdés, Juan José Zuñiga, Laura Y. Sánchez-López, Virginia Aleyda Healthcare (Basel) Review With the appearance of new viruses and infectious diseases (ID) such as COVID-19 in 2019, as well as the lack of specific pharmacological tools for the management of patients with severe complications or comorbidities, it is important to search for adjuvant treatments that help improve the prognosis of infectious disease patients. It is also important that these treatments limit the oxidative and hyperinflammatory damage caused as a response to pathogenic agents, since, in some cases, an inflammatory syndrome may develop that worsens the patient’s prognosis. The potential benefits of complementary nutrients and dietary interventions in the treatment of pathological processes in which oxidative stress and inflammation play a fundamental role have been widely evaluated. Coenzyme Q10 (CoQ10) is a supplement that has been shown to protect cells and be effective in cardiovascular diseases and obesity. Additionally, some studies have proposed it as a possible adjuvant treatment in viral infections. Preclinical and clinical studies have shown that CoQ10 has anti-inflammatory and antioxidant effects, and effects on mitochondrial dysfunction, which have been linked to the inflammatory response. MDPI 2022-03-07 /pmc/articles/PMC8953254/ /pubmed/35326965 http://dx.doi.org/10.3390/healthcare10030487 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sifuentes-Franco, Sonia Sánchez-Macías, Dellaneira Carolina Carrillo-Ibarra, Sandra Rivera-Valdés, Juan José Zuñiga, Laura Y. Sánchez-López, Virginia Aleyda Antioxidant and Anti-Inflammatory Effects of Coenzyme Q10 Supplementation on Infectious Diseases |
title | Antioxidant and Anti-Inflammatory Effects of Coenzyme Q10 Supplementation on Infectious Diseases |
title_full | Antioxidant and Anti-Inflammatory Effects of Coenzyme Q10 Supplementation on Infectious Diseases |
title_fullStr | Antioxidant and Anti-Inflammatory Effects of Coenzyme Q10 Supplementation on Infectious Diseases |
title_full_unstemmed | Antioxidant and Anti-Inflammatory Effects of Coenzyme Q10 Supplementation on Infectious Diseases |
title_short | Antioxidant and Anti-Inflammatory Effects of Coenzyme Q10 Supplementation on Infectious Diseases |
title_sort | antioxidant and anti-inflammatory effects of coenzyme q10 supplementation on infectious diseases |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953254/ https://www.ncbi.nlm.nih.gov/pubmed/35326965 http://dx.doi.org/10.3390/healthcare10030487 |
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