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Function of Nuclear Pore Complexes in Regulation of Plant Defense Signaling

In eukaryotes, the nucleus is the regulatory center of cytogenetics and metabolism, and it is critical for fundamental biological processes, including DNA replication and transcription, protein synthesis, and biological macromolecule transportation. The eukaryotic nucleus is surrounded by a lipid bi...

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Autores principales: Wu, Xi, Han, Junyou, Guo, Changkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953349/
https://www.ncbi.nlm.nih.gov/pubmed/35328452
http://dx.doi.org/10.3390/ijms23063031
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author Wu, Xi
Han, Junyou
Guo, Changkui
author_facet Wu, Xi
Han, Junyou
Guo, Changkui
author_sort Wu, Xi
collection PubMed
description In eukaryotes, the nucleus is the regulatory center of cytogenetics and metabolism, and it is critical for fundamental biological processes, including DNA replication and transcription, protein synthesis, and biological macromolecule transportation. The eukaryotic nucleus is surrounded by a lipid bilayer called the nuclear envelope (NE), which creates a microenvironment for sophisticated cellular processes. The NE is perforated by the nuclear pore complex (NPC), which is the channel for biological macromolecule bi-directional transport between the nucleus and cytoplasm. It is well known that NPC is the spatial designer of the genome and the manager of genomic function. Moreover, the NPC is considered to be a platform for the continual adaptation and evolution of eukaryotes. So far, a number of nucleoporins required for plant-defense processes have been identified. Here, we first provide an overview of NPC organization in plants, and then discuss recent findings in the plant NPC to elaborate on and dissect the distinct defensive functions of different NPC subcomponents in plant immune defense, growth and development, hormone signaling, and temperature response. Nucleoporins located in different components of NPC have their unique functions, and the link between the NPC and nucleocytoplasmic trafficking promotes crosstalk of different defense signals in plants. It is necessary to explore appropriate components of the NPC as potential targets for the breeding of high-quality and broad spectrum resistance crop varieties.
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spelling pubmed-89533492022-03-26 Function of Nuclear Pore Complexes in Regulation of Plant Defense Signaling Wu, Xi Han, Junyou Guo, Changkui Int J Mol Sci Review In eukaryotes, the nucleus is the regulatory center of cytogenetics and metabolism, and it is critical for fundamental biological processes, including DNA replication and transcription, protein synthesis, and biological macromolecule transportation. The eukaryotic nucleus is surrounded by a lipid bilayer called the nuclear envelope (NE), which creates a microenvironment for sophisticated cellular processes. The NE is perforated by the nuclear pore complex (NPC), which is the channel for biological macromolecule bi-directional transport between the nucleus and cytoplasm. It is well known that NPC is the spatial designer of the genome and the manager of genomic function. Moreover, the NPC is considered to be a platform for the continual adaptation and evolution of eukaryotes. So far, a number of nucleoporins required for plant-defense processes have been identified. Here, we first provide an overview of NPC organization in plants, and then discuss recent findings in the plant NPC to elaborate on and dissect the distinct defensive functions of different NPC subcomponents in plant immune defense, growth and development, hormone signaling, and temperature response. Nucleoporins located in different components of NPC have their unique functions, and the link between the NPC and nucleocytoplasmic trafficking promotes crosstalk of different defense signals in plants. It is necessary to explore appropriate components of the NPC as potential targets for the breeding of high-quality and broad spectrum resistance crop varieties. MDPI 2022-03-11 /pmc/articles/PMC8953349/ /pubmed/35328452 http://dx.doi.org/10.3390/ijms23063031 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Wu, Xi
Han, Junyou
Guo, Changkui
Function of Nuclear Pore Complexes in Regulation of Plant Defense Signaling
title Function of Nuclear Pore Complexes in Regulation of Plant Defense Signaling
title_full Function of Nuclear Pore Complexes in Regulation of Plant Defense Signaling
title_fullStr Function of Nuclear Pore Complexes in Regulation of Plant Defense Signaling
title_full_unstemmed Function of Nuclear Pore Complexes in Regulation of Plant Defense Signaling
title_short Function of Nuclear Pore Complexes in Regulation of Plant Defense Signaling
title_sort function of nuclear pore complexes in regulation of plant defense signaling
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953349/
https://www.ncbi.nlm.nih.gov/pubmed/35328452
http://dx.doi.org/10.3390/ijms23063031
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