Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis

AIMS: Hepatic capillaries are lined with specialized liver sinusoidal endothelial cells (LSECs) which support macromolecule passage to hepatocytes and prevent fibrosis by keeping hepatic stellate cells (HSCs) quiescent. LSEC specialization is co-determined by transcription factors. The zinc-finger E...

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Detalles Bibliográficos
Autores principales: de Haan, Willeke, Dheedene, Wouter, Apelt, Katerina, Décombas-Deschamps, Sofiane, Vinckier, Stefan, Verhulst, Stefaan, Conidi, Andrea, Deffieux, Thomas, Staring, Michael W, Vandervoort, Petra, Caluwé, Ellen, Lox, Marleen, Mannaerts, Inge, Takagi, Tsuyoshi, Jaekers, Joris, Berx, Geert, Haigh, Jody, Topal, Baki, Zwijsen, An, Higashi, Yujiro, van Grunsven, Leo A, van IJcken, Wilfred F J, Mulugeta, Eskeatnaf, Tanter, Mickael, Lebrin, Franck P G, Huylebroeck, Danny, Luttun, Aernout
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953454/
https://www.ncbi.nlm.nih.gov/pubmed/33909875
http://dx.doi.org/10.1093/cvr/cvab148

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