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Infection of Human Endothelial Cells with Lassa Virus Induces Early but Transient Activation and Low Type I IFN Response Compared to the Closely-Related Nonpathogenic Mopeia Virus
Lassa virus (LASV), an Old World arenavirus, is responsible for hemorrhagic fevers in western Africa. The privileged tropism of LASV for endothelial cells combined with a dysregulated inflammatory response are the main cause of the increase in vascular permeability observed during the disease. Mopei...
Autores principales: | Merabet, Othmann, Pietrosemoli, Natalia, Perthame, Emeline, Armengaud, Jean, Gaillard, Jean-Charles, Borges-Cardoso, Virginie, Daniau, Maïlys, Legras-Lachuer, Catherine, Carnec, Xavier, Baize, Sylvain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953476/ https://www.ncbi.nlm.nih.gov/pubmed/35337059 http://dx.doi.org/10.3390/v14030652 |
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