E-Volve: understanding the impact of mutations in SARS-CoV-2 variants spike protein on antibodies and ACE2 affinity through patterns of chemical interactions at protein interfaces

BACKGROUND: The SARS-CoV-2 pandemic reverberated, posing health and social hygiene obstacles throughout the globe. Mutant lineages of the virus have concerned scientists because of convergent amino acid alterations, mainly on the viral spike protein. Studies have shown that mutants have diminished a...

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Detalles Bibliográficos
Autores principales: Dos Santos, Vitor Pimentel, Rodrigues, André, Dutra, Gabriel, Bastos, Luana, Mariano, Diego, Mendonça, José Gutembergue, Lobo, Yan Jerônimo Gomes, Mendes, Eduardo, Maia, Giovana, Machado, Karina dos Santos, Werhli, Adriano Velasque, Rocha, Gerd, de Lima, Leonardo Henrique França, de Melo-Minardi, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953562/
https://www.ncbi.nlm.nih.gov/pubmed/35341044
http://dx.doi.org/10.7717/peerj.13099

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