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Selective measurement of NAPE-PLD activity via a PLA(1/2)-resistant fluorogenic N-acyl-phosphatidylethanolamine analog

N-acyl-phosphatidylethanolamine (NAPE)-hydrolyzing phospholipase D (NAPE-PLD) is a zinc metallohydrolase enzyme that converts NAPEs to bioactive N-acyl-ethanolamides. Altered NAPE-PLD activity may contribute to pathogenesis of obesity, diabetes, atherosclerosis, and neurological diseases. Selective...

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Detalles Bibliográficos
Autores principales:	Zarrow, Jonah E., Tian, Jianhua, Dutter, Brendan, Kim, Kwangho, Doran, Amanda C., Sulikowski, Gary A., Davies, Sean S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953660/ https://www.ncbi.nlm.nih.gov/pubmed/34843683 http://dx.doi.org/10.1016/j.jlr.2021.100156

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