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Lipid droplet-mitochondria coupling via perilipin 5 augments respiratory capacity but is dispensable for FA oxidation

Disturbances in lipid homeostasis can cause mitochondrial dysfunction and lipotoxicity. Perilipin 5 (PLIN5) decorates intracellular lipid droplets (LDs) in oxidative tissues and controls triacylglycerol (TG) turnover via its interactions with adipose triglyceride lipase and the adipose triglyceride...

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Detalles Bibliográficos
Autores principales:	Kien, Benedikt, Kolleritsch, Stephanie, Kunowska, Natalia, Heier, Christoph, Chalhoub, Gabriel, Tilp, Anna, Wolinski, Heimo, Stelzl, Ulrich, Haemmerle, Guenter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953689/ https://www.ncbi.nlm.nih.gov/pubmed/35065923 http://dx.doi.org/10.1016/j.jlr.2022.100172

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