Elevated granulocyte-colony stimulating factor and hematopoietic stem cell mobilization in Niemann-Pick type C1 disease

Niemann-Pick type C1 (NPC1) disease is a progressive lysosomal storage disorder caused by mutations of the NPC1 gene. While neurodegeneration is the most severe symptom, a large proportion of NPC1 patients also present with splenomegaly, which has been attributed to cholesterol and glycosphingolipid...

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Detalles Bibliográficos
Autores principales: Groenen, Anouk G., La Rose, Anouk M., Li, Mengying, Bazioti, Venetia, Svendsen, Arthur F., Kloosterhuis, Niels J., Ausema, Albertina, Pranger, Alle, Heiner-Fokkema, M. Rebecca, Niezen-Koning, Klary E., Houben, Tom, Shiri-Sverdlov, Ronit, Westerterp, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953690/
https://www.ncbi.nlm.nih.gov/pubmed/35007562
http://dx.doi.org/10.1016/j.jlr.2021.100167

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