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Regulation of ABCA1 by AMD-Associated Genetic Variants and Hypoxia in iPSC-RPE
Age-related macular degeneration (AMD) is a progressive disease of the macula characterized by atrophy of the retinal pigment epithelium (RPE) and photoreceptor degeneration, leading to severe vision loss at advanced stages in the elderly population. Impaired reverse cholesterol transport (RCT) as w...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953808/ https://www.ncbi.nlm.nih.gov/pubmed/35328615 http://dx.doi.org/10.3390/ijms23063194 |