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Regulation of ABCA1 by AMD-Associated Genetic Variants and Hypoxia in iPSC-RPE

Age-related macular degeneration (AMD) is a progressive disease of the macula characterized by atrophy of the retinal pigment epithelium (RPE) and photoreceptor degeneration, leading to severe vision loss at advanced stages in the elderly population. Impaired reverse cholesterol transport (RCT) as w...

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Detalles Bibliográficos
Autores principales:	Peters, Florian, Ebner, Lynn J. A., Atac, David, Maggi, Jordi, Berger, Wolfgang, den Hollander, Anneke I., Grimm, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953808/ https://www.ncbi.nlm.nih.gov/pubmed/35328615 http://dx.doi.org/10.3390/ijms23063194

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