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The 2020 update on anaphylaxis in paediatric population
The objective of the review is to present recent updates on anaphylaxis in paediatric population worldwide. The article summarizes the results of epidemiological studies, diagnostic methods and treatments. We present a new WAO definition of anaphylaxis (2019), which broader criteria excluding dermal...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953896/ https://www.ncbi.nlm.nih.gov/pubmed/35369644 http://dx.doi.org/10.5114/ada.2021.103327 |
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author | Tarczoń, Izabela Cichocka-Jarosz, Ewa Knapp, Anna Kwinta, Przemko |
author_facet | Tarczoń, Izabela Cichocka-Jarosz, Ewa Knapp, Anna Kwinta, Przemko |
author_sort | Tarczoń, Izabela |
collection | PubMed |
description | The objective of the review is to present recent updates on anaphylaxis in paediatric population worldwide. The article summarizes the results of epidemiological studies, diagnostic methods and treatments. We present a new WAO definition of anaphylaxis (2019), which broader criteria excluding dermal symptoms should facilitate faster life-saving adrenaline use. Adrenaline remains the best treatment to manage severe symptoms and to prevent biphasic reactions. There is ongoing effort to increase adrenaline use, such as modified autoinjectors, individual training, and diversified dosing. There are five independent risk factors of lethal anaphylaxis in children, including history of asthma, almost immediate onset of symptoms, unwell appearance, tachycardia and hypotension. We also report improvements in diagnostics, like component-resolved diagnostics, and novel therapies stimulating immunotolerance. We signal the development of ICD-11 with updated coding of anaphylaxis, which corresponds better to clinical observations. |
format | Online Article Text |
id | pubmed-8953896 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-89538962022-03-31 The 2020 update on anaphylaxis in paediatric population Tarczoń, Izabela Cichocka-Jarosz, Ewa Knapp, Anna Kwinta, Przemko Postepy Dermatol Alergol Review Paper The objective of the review is to present recent updates on anaphylaxis in paediatric population worldwide. The article summarizes the results of epidemiological studies, diagnostic methods and treatments. We present a new WAO definition of anaphylaxis (2019), which broader criteria excluding dermal symptoms should facilitate faster life-saving adrenaline use. Adrenaline remains the best treatment to manage severe symptoms and to prevent biphasic reactions. There is ongoing effort to increase adrenaline use, such as modified autoinjectors, individual training, and diversified dosing. There are five independent risk factors of lethal anaphylaxis in children, including history of asthma, almost immediate onset of symptoms, unwell appearance, tachycardia and hypotension. We also report improvements in diagnostics, like component-resolved diagnostics, and novel therapies stimulating immunotolerance. We signal the development of ICD-11 with updated coding of anaphylaxis, which corresponds better to clinical observations. Termedia Publishing House 2021-02-06 2022-02 /pmc/articles/PMC8953896/ /pubmed/35369644 http://dx.doi.org/10.5114/ada.2021.103327 Text en Copyright © 2022 Termedia https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). License (http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/) ) |
spellingShingle | Review Paper Tarczoń, Izabela Cichocka-Jarosz, Ewa Knapp, Anna Kwinta, Przemko The 2020 update on anaphylaxis in paediatric population |
title | The 2020 update on anaphylaxis in paediatric population |
title_full | The 2020 update on anaphylaxis in paediatric population |
title_fullStr | The 2020 update on anaphylaxis in paediatric population |
title_full_unstemmed | The 2020 update on anaphylaxis in paediatric population |
title_short | The 2020 update on anaphylaxis in paediatric population |
title_sort | 2020 update on anaphylaxis in paediatric population |
topic | Review Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953896/ https://www.ncbi.nlm.nih.gov/pubmed/35369644 http://dx.doi.org/10.5114/ada.2021.103327 |
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