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Age Dependent Epidemic Modeling of COVID-19 Outbreak in Kuwait, France, and Cameroon

Revisiting the classical model by Ross and Kermack-McKendrick, the Susceptible–Infectious–Recovered (SIR) model used to formalize the COVID-19 epidemic, requires improvements which will be the subject of this article. The heterogeneity in the age of the populations concerned leads to considering mod...

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Autores principales: Oshinubi, Kayode, Buhamra, Sana S., Al-Kandari, Noriah M., Waku, Jules, Rachdi, Mustapha, Demongeot, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954002/
https://www.ncbi.nlm.nih.gov/pubmed/35326960
http://dx.doi.org/10.3390/healthcare10030482
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author Oshinubi, Kayode
Buhamra, Sana S.
Al-Kandari, Noriah M.
Waku, Jules
Rachdi, Mustapha
Demongeot, Jacques
author_facet Oshinubi, Kayode
Buhamra, Sana S.
Al-Kandari, Noriah M.
Waku, Jules
Rachdi, Mustapha
Demongeot, Jacques
author_sort Oshinubi, Kayode
collection PubMed
description Revisiting the classical model by Ross and Kermack-McKendrick, the Susceptible–Infectious–Recovered (SIR) model used to formalize the COVID-19 epidemic, requires improvements which will be the subject of this article. The heterogeneity in the age of the populations concerned leads to considering models in age groups with specific susceptibilities, which makes the prediction problem more difficult. Basically, there are three age groups of interest which are, respectively, 0–19 years, 20–64 years, and >64 years, but in this article, we only consider two (20–64 years and >64 years) age groups because the group 0–19 years is widely seen as being less infected by the virus since this age group had a low infection rate throughout the pandemic era of this study, especially the countries under consideration. In this article, we proposed a new mathematical age-dependent (Susceptible–Infectious–Goneanewsusceptible–Recovered (SIGR)) model for the COVID-19 outbreak and performed some mathematical analyses by showing the positivity, boundedness, stability, existence, and uniqueness of the solution. We performed numerical simulations of the model with parameters from Kuwait, France, and Cameroon. We discuss the role of these different parameters used in the model; namely, vaccination on the epidemic dynamics. We open a new perspective of improving an age-dependent model and its application to observed data and parameters.
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spelling pubmed-89540022022-03-26 Age Dependent Epidemic Modeling of COVID-19 Outbreak in Kuwait, France, and Cameroon Oshinubi, Kayode Buhamra, Sana S. Al-Kandari, Noriah M. Waku, Jules Rachdi, Mustapha Demongeot, Jacques Healthcare (Basel) Article Revisiting the classical model by Ross and Kermack-McKendrick, the Susceptible–Infectious–Recovered (SIR) model used to formalize the COVID-19 epidemic, requires improvements which will be the subject of this article. The heterogeneity in the age of the populations concerned leads to considering models in age groups with specific susceptibilities, which makes the prediction problem more difficult. Basically, there are three age groups of interest which are, respectively, 0–19 years, 20–64 years, and >64 years, but in this article, we only consider two (20–64 years and >64 years) age groups because the group 0–19 years is widely seen as being less infected by the virus since this age group had a low infection rate throughout the pandemic era of this study, especially the countries under consideration. In this article, we proposed a new mathematical age-dependent (Susceptible–Infectious–Goneanewsusceptible–Recovered (SIGR)) model for the COVID-19 outbreak and performed some mathematical analyses by showing the positivity, boundedness, stability, existence, and uniqueness of the solution. We performed numerical simulations of the model with parameters from Kuwait, France, and Cameroon. We discuss the role of these different parameters used in the model; namely, vaccination on the epidemic dynamics. We open a new perspective of improving an age-dependent model and its application to observed data and parameters. MDPI 2022-03-04 /pmc/articles/PMC8954002/ /pubmed/35326960 http://dx.doi.org/10.3390/healthcare10030482 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Oshinubi, Kayode
Buhamra, Sana S.
Al-Kandari, Noriah M.
Waku, Jules
Rachdi, Mustapha
Demongeot, Jacques
Age Dependent Epidemic Modeling of COVID-19 Outbreak in Kuwait, France, and Cameroon
title Age Dependent Epidemic Modeling of COVID-19 Outbreak in Kuwait, France, and Cameroon
title_full Age Dependent Epidemic Modeling of COVID-19 Outbreak in Kuwait, France, and Cameroon
title_fullStr Age Dependent Epidemic Modeling of COVID-19 Outbreak in Kuwait, France, and Cameroon
title_full_unstemmed Age Dependent Epidemic Modeling of COVID-19 Outbreak in Kuwait, France, and Cameroon
title_short Age Dependent Epidemic Modeling of COVID-19 Outbreak in Kuwait, France, and Cameroon
title_sort age dependent epidemic modeling of covid-19 outbreak in kuwait, france, and cameroon
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954002/
https://www.ncbi.nlm.nih.gov/pubmed/35326960
http://dx.doi.org/10.3390/healthcare10030482
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