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Physical Quality of Life of Sepsis Survivor Severely Malnourished Children after Hospital Discharge: Findings from a Retrospective Chart Analysis

Background: Quality of life (QoL) among pediatric sepsis survivors in resource-limited countries is poorly understood. We aimed to evaluate the QoL among sepsis survivors, by comparing them with non-sepsis survivors three months after hospital discharge. Methodology: In this retrospective chart anal...

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Autores principales: Sarmin, Monira, Alam, Tahmina, Shaly, Nusrat Jahan, Jeorge, Didarul Haque, Afroze, Farzana, Shahrin, Lubaba, Shahunja, K. M., Ahmed, Tahmeed, Shahid, Abu Sadat Mohammad Sayeem Bin, Chisti, Mohammod Jobayer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954014/
https://www.ncbi.nlm.nih.gov/pubmed/35330130
http://dx.doi.org/10.3390/life12030379
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author Sarmin, Monira
Alam, Tahmina
Shaly, Nusrat Jahan
Jeorge, Didarul Haque
Afroze, Farzana
Shahrin, Lubaba
Shahunja, K. M.
Ahmed, Tahmeed
Shahid, Abu Sadat Mohammad Sayeem Bin
Chisti, Mohammod Jobayer
author_facet Sarmin, Monira
Alam, Tahmina
Shaly, Nusrat Jahan
Jeorge, Didarul Haque
Afroze, Farzana
Shahrin, Lubaba
Shahunja, K. M.
Ahmed, Tahmeed
Shahid, Abu Sadat Mohammad Sayeem Bin
Chisti, Mohammod Jobayer
author_sort Sarmin, Monira
collection PubMed
description Background: Quality of life (QoL) among pediatric sepsis survivors in resource-limited countries is poorly understood. We aimed to evaluate the QoL among sepsis survivors, by comparing them with non-sepsis survivors three months after hospital discharge. Methodology: In this retrospective chart analysis with a case–control design, we compared children having sepsis and non-sepsis at hospital admission and during their post-hospitalization life, where the study population was derived from a hospital cohort of 405 severely malnourished children having pneumonia. Results: The median age (months, inter-quartile range) of the children having sepsis and non-sepsis was 10 (5, 17) and 9 (5, 18), respectively. Approximately half of the children among the sepsis survivors had new episodes of respiratory symptoms at home. Though death was significantly higher (15.8% vs. 2.7%, p ≤ 0.001) at admission among the sepsis group, deaths during post-hospitalization life (7.8% vs. 8.8%, p = 0.878) were comparable. A verbal autopsy revealed that before death, most of the children from the sepsis group had respiratory complaints, whereas gastrointestinal complaints were more common among the non-sepsis group. Conclusions: Pediatric sepsis is life-threatening both during hospitalization and post-discharge. The QoL after sepsis is compromised, including re-hospitalization and the development of new episodes of respiratory symptoms especially before death.
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spelling pubmed-89540142022-03-26 Physical Quality of Life of Sepsis Survivor Severely Malnourished Children after Hospital Discharge: Findings from a Retrospective Chart Analysis Sarmin, Monira Alam, Tahmina Shaly, Nusrat Jahan Jeorge, Didarul Haque Afroze, Farzana Shahrin, Lubaba Shahunja, K. M. Ahmed, Tahmeed Shahid, Abu Sadat Mohammad Sayeem Bin Chisti, Mohammod Jobayer Life (Basel) Article Background: Quality of life (QoL) among pediatric sepsis survivors in resource-limited countries is poorly understood. We aimed to evaluate the QoL among sepsis survivors, by comparing them with non-sepsis survivors three months after hospital discharge. Methodology: In this retrospective chart analysis with a case–control design, we compared children having sepsis and non-sepsis at hospital admission and during their post-hospitalization life, where the study population was derived from a hospital cohort of 405 severely malnourished children having pneumonia. Results: The median age (months, inter-quartile range) of the children having sepsis and non-sepsis was 10 (5, 17) and 9 (5, 18), respectively. Approximately half of the children among the sepsis survivors had new episodes of respiratory symptoms at home. Though death was significantly higher (15.8% vs. 2.7%, p ≤ 0.001) at admission among the sepsis group, deaths during post-hospitalization life (7.8% vs. 8.8%, p = 0.878) were comparable. A verbal autopsy revealed that before death, most of the children from the sepsis group had respiratory complaints, whereas gastrointestinal complaints were more common among the non-sepsis group. Conclusions: Pediatric sepsis is life-threatening both during hospitalization and post-discharge. The QoL after sepsis is compromised, including re-hospitalization and the development of new episodes of respiratory symptoms especially before death. MDPI 2022-03-05 /pmc/articles/PMC8954014/ /pubmed/35330130 http://dx.doi.org/10.3390/life12030379 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sarmin, Monira
Alam, Tahmina
Shaly, Nusrat Jahan
Jeorge, Didarul Haque
Afroze, Farzana
Shahrin, Lubaba
Shahunja, K. M.
Ahmed, Tahmeed
Shahid, Abu Sadat Mohammad Sayeem Bin
Chisti, Mohammod Jobayer
Physical Quality of Life of Sepsis Survivor Severely Malnourished Children after Hospital Discharge: Findings from a Retrospective Chart Analysis
title Physical Quality of Life of Sepsis Survivor Severely Malnourished Children after Hospital Discharge: Findings from a Retrospective Chart Analysis
title_full Physical Quality of Life of Sepsis Survivor Severely Malnourished Children after Hospital Discharge: Findings from a Retrospective Chart Analysis
title_fullStr Physical Quality of Life of Sepsis Survivor Severely Malnourished Children after Hospital Discharge: Findings from a Retrospective Chart Analysis
title_full_unstemmed Physical Quality of Life of Sepsis Survivor Severely Malnourished Children after Hospital Discharge: Findings from a Retrospective Chart Analysis
title_short Physical Quality of Life of Sepsis Survivor Severely Malnourished Children after Hospital Discharge: Findings from a Retrospective Chart Analysis
title_sort physical quality of life of sepsis survivor severely malnourished children after hospital discharge: findings from a retrospective chart analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954014/
https://www.ncbi.nlm.nih.gov/pubmed/35330130
http://dx.doi.org/10.3390/life12030379
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