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Toxic Mechanism and Biological Detoxification of Fumonisins

Food safety is related to the national economy and people’s livelihood. Fumonisins are widely found in animal feed, feed raw materials, and human food. This can not only cause economic losses in animal husbandry but can also have carcinogenicity or teratogenicity and can be left in animal meat, eggs...

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Detalles Bibliográficos
Autores principales: Qu, Linkai, Wang, Lei, Ji, Hao, Fang, Yimeng, Lei, Pengyu, Zhang, Xingxing, Jin, Libo, Sun, Da, Dong, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954241/
https://www.ncbi.nlm.nih.gov/pubmed/35324679
http://dx.doi.org/10.3390/toxins14030182
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author Qu, Linkai
Wang, Lei
Ji, Hao
Fang, Yimeng
Lei, Pengyu
Zhang, Xingxing
Jin, Libo
Sun, Da
Dong, Hao
author_facet Qu, Linkai
Wang, Lei
Ji, Hao
Fang, Yimeng
Lei, Pengyu
Zhang, Xingxing
Jin, Libo
Sun, Da
Dong, Hao
author_sort Qu, Linkai
collection PubMed
description Food safety is related to the national economy and people’s livelihood. Fumonisins are widely found in animal feed, feed raw materials, and human food. This can not only cause economic losses in animal husbandry but can also have carcinogenicity or teratogenicity and can be left in animal meat, eggs, and milk which may enter the human body and pose a serious threat to human health. Although there are many strategies to prevent fumonisins from entering the food chain, the traditional physical and chemical methods of mycotoxin removal have some disadvantages, such as an unstable effect, large nutrient loss, impact on the palatability of feed, and difficulty in mass production. As a safe, efficient, and environmentally friendly detoxification technology, biological detoxification attracts more and more attention from researchers and is gradually becoming an accepted technique. This work summarizes the toxic mechanism of fumonisins and highlights the advances of fumonisins in the detoxification of biological antioxidants, antagonistic microorganisms, and degradation mechanisms. Finally, the future challenges and focus of the biological control and degradation of fumonisins are discussed.
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spelling pubmed-89542412022-03-26 Toxic Mechanism and Biological Detoxification of Fumonisins Qu, Linkai Wang, Lei Ji, Hao Fang, Yimeng Lei, Pengyu Zhang, Xingxing Jin, Libo Sun, Da Dong, Hao Toxins (Basel) Review Food safety is related to the national economy and people’s livelihood. Fumonisins are widely found in animal feed, feed raw materials, and human food. This can not only cause economic losses in animal husbandry but can also have carcinogenicity or teratogenicity and can be left in animal meat, eggs, and milk which may enter the human body and pose a serious threat to human health. Although there are many strategies to prevent fumonisins from entering the food chain, the traditional physical and chemical methods of mycotoxin removal have some disadvantages, such as an unstable effect, large nutrient loss, impact on the palatability of feed, and difficulty in mass production. As a safe, efficient, and environmentally friendly detoxification technology, biological detoxification attracts more and more attention from researchers and is gradually becoming an accepted technique. This work summarizes the toxic mechanism of fumonisins and highlights the advances of fumonisins in the detoxification of biological antioxidants, antagonistic microorganisms, and degradation mechanisms. Finally, the future challenges and focus of the biological control and degradation of fumonisins are discussed. MDPI 2022-03-01 /pmc/articles/PMC8954241/ /pubmed/35324679 http://dx.doi.org/10.3390/toxins14030182 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Qu, Linkai
Wang, Lei
Ji, Hao
Fang, Yimeng
Lei, Pengyu
Zhang, Xingxing
Jin, Libo
Sun, Da
Dong, Hao
Toxic Mechanism and Biological Detoxification of Fumonisins
title Toxic Mechanism and Biological Detoxification of Fumonisins
title_full Toxic Mechanism and Biological Detoxification of Fumonisins
title_fullStr Toxic Mechanism and Biological Detoxification of Fumonisins
title_full_unstemmed Toxic Mechanism and Biological Detoxification of Fumonisins
title_short Toxic Mechanism and Biological Detoxification of Fumonisins
title_sort toxic mechanism and biological detoxification of fumonisins
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954241/
https://www.ncbi.nlm.nih.gov/pubmed/35324679
http://dx.doi.org/10.3390/toxins14030182
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