The Emerging Roles of Intracellular PCSK9 and Their Implications in Endoplasmic Reticulum Stress and Metabolic Diseases

The importance of the proprotein convertase subtilisin/kexin type-9 (PCSK9) gene was quickly recognized by the scientific community as the third locus for familial hypercholesterolemia. By promoting the degradation of the low-density lipoprotein receptor (LDLR), secreted PCSK9 protein plays a vital...

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Detalles Bibliográficos
Autores principales: Lebeau, Paul F., Platko, Khrystyna, Byun, Jae Hyun, Makda, Yumna, Austin, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954296/
https://www.ncbi.nlm.nih.gov/pubmed/35323658
http://dx.doi.org/10.3390/metabo12030215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954296/
https://www.ncbi.nlm.nih.gov/pubmed/35323658
http://dx.doi.org/10.3390/metabo12030215

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