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Increased Heparanase Levels in Urine during Acute Puumala Orthohantavirus Infection Are Associated with Disease Severity

Old–world orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS), characterized by acute kidney injury (AKI) with transient proteinuria. It seems plausible that proteinuria during acute HFRS is mediated by the disruption of the glomerular filtration barrier (GFB) due to vascular leakag...

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Detalles Bibliográficos
Autores principales:	Cabrera, Luz E., Schmotz, Constanze, Saleem, Moin A., Lehtonen, Sanna, Vapalahti, Olli, Vaheri, Antti, Mäkelä, Satu, Mustonen, Jukka, Strandin, Tomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954369/ https://www.ncbi.nlm.nih.gov/pubmed/35336857 http://dx.doi.org/10.3390/v14030450

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