One-Pot Synthesis and Molecular Modeling Studies of New Bioactive Spiro-Oxindoles Based on Uracil Derivatives as SARS-CoV-2 Inhibitors Targeting RNA Polymerase and Spike Glycoprotein

The first outbreak in Wuhan, China, in December 2019 was reported about severe acute coronaviral syndrome 2 (SARS-CoV-2). The global coronavirus disease 2019 (COVID-19) pandemic in 2020 resulted in an extremely high potential for dissemination. No drugs are validated in large-scale studies for signi...

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Detalles Bibliográficos
Autores principales: El-Kalyoubi, Samar A., Ragab, Ahmed, Abu Ali, Ola A., Ammar, Yousry A., Seadawy, Mohamed G., Ahmed, Aya, Fayed, Eman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954694/
https://www.ncbi.nlm.nih.gov/pubmed/35337173
http://dx.doi.org/10.3390/ph15030376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954694/
https://www.ncbi.nlm.nih.gov/pubmed/35337173
http://dx.doi.org/10.3390/ph15030376

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