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Viscoelastic Particle Focusing and Separation in a Spiral Channel

As one type of non-Newtonian fluid, viscoelastic fluids exhibit unique properties that contribute to particle lateral migration in confined microfluidic channels, leading to opportunities for particle manipulation and separation. In this paper, particle focusing in viscoelastic flow is studied in a...

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Autores principales: Feng, Haidong, Jafek, Alexander R., Wang, Bonan, Brady, Hayden, Magda, Jules J., Gale, Bruce K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954746/
https://www.ncbi.nlm.nih.gov/pubmed/35334653
http://dx.doi.org/10.3390/mi13030361
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author Feng, Haidong
Jafek, Alexander R.
Wang, Bonan
Brady, Hayden
Magda, Jules J.
Gale, Bruce K.
author_facet Feng, Haidong
Jafek, Alexander R.
Wang, Bonan
Brady, Hayden
Magda, Jules J.
Gale, Bruce K.
author_sort Feng, Haidong
collection PubMed
description As one type of non-Newtonian fluid, viscoelastic fluids exhibit unique properties that contribute to particle lateral migration in confined microfluidic channels, leading to opportunities for particle manipulation and separation. In this paper, particle focusing in viscoelastic flow is studied in a wide range of polyethylene glycol (PEO) concentrations in aqueous solutions. Polystyrene beads with diameters from 3 to 20 μm are tested, and the variation of particle focusing position is explained by the coeffects of inertial flow, viscoelastic flow, and Dean flow. We showed that particle focusing position can be predicted by analyzing the force balance in the microchannel, and that particle separation resolution can be improved in viscoelastic flows.
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spelling pubmed-89547462022-03-26 Viscoelastic Particle Focusing and Separation in a Spiral Channel Feng, Haidong Jafek, Alexander R. Wang, Bonan Brady, Hayden Magda, Jules J. Gale, Bruce K. Micromachines (Basel) Article As one type of non-Newtonian fluid, viscoelastic fluids exhibit unique properties that contribute to particle lateral migration in confined microfluidic channels, leading to opportunities for particle manipulation and separation. In this paper, particle focusing in viscoelastic flow is studied in a wide range of polyethylene glycol (PEO) concentrations in aqueous solutions. Polystyrene beads with diameters from 3 to 20 μm are tested, and the variation of particle focusing position is explained by the coeffects of inertial flow, viscoelastic flow, and Dean flow. We showed that particle focusing position can be predicted by analyzing the force balance in the microchannel, and that particle separation resolution can be improved in viscoelastic flows. MDPI 2022-02-25 /pmc/articles/PMC8954746/ /pubmed/35334653 http://dx.doi.org/10.3390/mi13030361 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Feng, Haidong
Jafek, Alexander R.
Wang, Bonan
Brady, Hayden
Magda, Jules J.
Gale, Bruce K.
Viscoelastic Particle Focusing and Separation in a Spiral Channel
title Viscoelastic Particle Focusing and Separation in a Spiral Channel
title_full Viscoelastic Particle Focusing and Separation in a Spiral Channel
title_fullStr Viscoelastic Particle Focusing and Separation in a Spiral Channel
title_full_unstemmed Viscoelastic Particle Focusing and Separation in a Spiral Channel
title_short Viscoelastic Particle Focusing and Separation in a Spiral Channel
title_sort viscoelastic particle focusing and separation in a spiral channel
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954746/
https://www.ncbi.nlm.nih.gov/pubmed/35334653
http://dx.doi.org/10.3390/mi13030361
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