Cargando…
Viscoelastic Particle Focusing and Separation in a Spiral Channel
As one type of non-Newtonian fluid, viscoelastic fluids exhibit unique properties that contribute to particle lateral migration in confined microfluidic channels, leading to opportunities for particle manipulation and separation. In this paper, particle focusing in viscoelastic flow is studied in a...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954746/ https://www.ncbi.nlm.nih.gov/pubmed/35334653 http://dx.doi.org/10.3390/mi13030361 |
_version_ | 1784676169482764288 |
---|---|
author | Feng, Haidong Jafek, Alexander R. Wang, Bonan Brady, Hayden Magda, Jules J. Gale, Bruce K. |
author_facet | Feng, Haidong Jafek, Alexander R. Wang, Bonan Brady, Hayden Magda, Jules J. Gale, Bruce K. |
author_sort | Feng, Haidong |
collection | PubMed |
description | As one type of non-Newtonian fluid, viscoelastic fluids exhibit unique properties that contribute to particle lateral migration in confined microfluidic channels, leading to opportunities for particle manipulation and separation. In this paper, particle focusing in viscoelastic flow is studied in a wide range of polyethylene glycol (PEO) concentrations in aqueous solutions. Polystyrene beads with diameters from 3 to 20 μm are tested, and the variation of particle focusing position is explained by the coeffects of inertial flow, viscoelastic flow, and Dean flow. We showed that particle focusing position can be predicted by analyzing the force balance in the microchannel, and that particle separation resolution can be improved in viscoelastic flows. |
format | Online Article Text |
id | pubmed-8954746 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89547462022-03-26 Viscoelastic Particle Focusing and Separation in a Spiral Channel Feng, Haidong Jafek, Alexander R. Wang, Bonan Brady, Hayden Magda, Jules J. Gale, Bruce K. Micromachines (Basel) Article As one type of non-Newtonian fluid, viscoelastic fluids exhibit unique properties that contribute to particle lateral migration in confined microfluidic channels, leading to opportunities for particle manipulation and separation. In this paper, particle focusing in viscoelastic flow is studied in a wide range of polyethylene glycol (PEO) concentrations in aqueous solutions. Polystyrene beads with diameters from 3 to 20 μm are tested, and the variation of particle focusing position is explained by the coeffects of inertial flow, viscoelastic flow, and Dean flow. We showed that particle focusing position can be predicted by analyzing the force balance in the microchannel, and that particle separation resolution can be improved in viscoelastic flows. MDPI 2022-02-25 /pmc/articles/PMC8954746/ /pubmed/35334653 http://dx.doi.org/10.3390/mi13030361 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Feng, Haidong Jafek, Alexander R. Wang, Bonan Brady, Hayden Magda, Jules J. Gale, Bruce K. Viscoelastic Particle Focusing and Separation in a Spiral Channel |
title | Viscoelastic Particle Focusing and Separation in a Spiral Channel |
title_full | Viscoelastic Particle Focusing and Separation in a Spiral Channel |
title_fullStr | Viscoelastic Particle Focusing and Separation in a Spiral Channel |
title_full_unstemmed | Viscoelastic Particle Focusing and Separation in a Spiral Channel |
title_short | Viscoelastic Particle Focusing and Separation in a Spiral Channel |
title_sort | viscoelastic particle focusing and separation in a spiral channel |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954746/ https://www.ncbi.nlm.nih.gov/pubmed/35334653 http://dx.doi.org/10.3390/mi13030361 |
work_keys_str_mv | AT fenghaidong viscoelasticparticlefocusingandseparationinaspiralchannel AT jafekalexanderr viscoelasticparticlefocusingandseparationinaspiralchannel AT wangbonan viscoelasticparticlefocusingandseparationinaspiralchannel AT bradyhayden viscoelasticparticlefocusingandseparationinaspiralchannel AT magdajulesj viscoelasticparticlefocusingandseparationinaspiralchannel AT galebrucek viscoelasticparticlefocusingandseparationinaspiralchannel |