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Decrease in ovarian reserve through the inhibition of SIRT1-mediated oxidative phosphorylation

Objective: To establish an oxidative stress-induced model of premature ovarian insufficiency (POI) and to explore the effect of SIRT1 and mitochondrial oxidative phosphorylation on the ovarian reserve. Methods: Mice were treated with intraperitoneal injections of 3-nitropropionic acid (3-NPA) at dif...

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Detalles Bibliográficos
Autores principales: Guo, Lu, Liu, Xiaocheng, Chen, Hua, Wang, Weigui, Gu, Chao, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954953/
https://www.ncbi.nlm.nih.gov/pubmed/35275845
http://dx.doi.org/10.18632/aging.203942

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