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Decrease in ovarian reserve through the inhibition of SIRT1-mediated oxidative phosphorylation

Objective: To establish an oxidative stress-induced model of premature ovarian insufficiency (POI) and to explore the effect of SIRT1 and mitochondrial oxidative phosphorylation on the ovarian reserve. Methods: Mice were treated with intraperitoneal injections of 3-nitropropionic acid (3-NPA) at dif...

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Detalles Bibliográficos
Autores principales:	Guo, Lu, Liu, Xiaocheng, Chen, Hua, Wang, Weigui, Gu, Chao, Li, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954953/ https://www.ncbi.nlm.nih.gov/pubmed/35275845 http://dx.doi.org/10.18632/aging.203942

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