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miRNA-29a inhibits atherosclerotic plaque formation by mediating macrophage autophagy via PI3K/AKT/mTOR pathway

Background: miR-29a plays a vital role in AS, but the relationship between the miR-29a-targeted PI3K signaling pathway and AS remains unclear. Therefore, this study was carried out. Methods: Gene expression profiles from the GEO database containing AS samples were analyzed. ApoE(−/−) mice and RAW264...

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Detalles Bibliográficos
Autores principales: Shao, Weihua, Wang, Suxing, Wang, Xiaoxi, Yao, Lixia, Yuan, Xiaoye, Huang, Dai, Lv, Bonan, Ye, Yuquan, Xue, Hongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954956/
https://www.ncbi.nlm.nih.gov/pubmed/35288486
http://dx.doi.org/10.18632/aging.203951