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Expression of the First Recombinant Anti-Tumoral Snake Venom Kunitz-Type Serine Protease Inhibitor

PIVL is a Kunitz-type serine protease inhibitor that was previously characterized from Tunisian snake venom, Macrovipera lebetina transmediterranea. It reduced glioblastoma cells’ development and significantly blocked angiogenesis in in-vitro and ex-vivo models. PIVL exerted these effects by interfe...

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Detalles Bibliográficos
Autores principales: Morjen, Maram, Moslah, Wassim, Touihri-Baraketi, Imen, Srairi-Abid, Najet, Luis, José, Marrakchi, Naziha, Jebali, Jed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955015/
https://www.ncbi.nlm.nih.gov/pubmed/35324668
http://dx.doi.org/10.3390/toxins14030170