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Neutralizing Monoclonal Antibody, mAb 10D8, Is an Effective Detoxicant against Abrin-a Both In Vitro and In Vivo

Abrin is a types II ribosome-inactivating protein (RIP) isolated from Abrus precatorious seeds, which comprises a catalytically active A chain and a lectin-like B chain linked by a disulfide bond. Four isotoxins of abrin have been reported with similar amino-acid composition but different cytotoxici...

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Detalles Bibliográficos
Autores principales:	Li, Zhi, Xu, Hua, Ma, Bo, Luo, Li, Guo, Lei, Zhang, Pingping, Zhao, Yong, Wang, Lili, Xie, Jianwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955035/ https://www.ncbi.nlm.nih.gov/pubmed/35324661 http://dx.doi.org/10.3390/toxins14030164

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