Cargando…

Identifying HSV-1 Inhibitors from Natural Compounds via Virtual Screening Targeting Surface Glycoprotein D

Herpes simplex virus (HSV) infections are a worldwide health problem in need of new effective treatments. Of particular interest is the identification of antiviral agents that act via different mechanisms compared to current drugs, as these could interact synergistically with first-line antiherpetic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Jiadai, Power, Helen, Miranda-Saksena, Monica, Valtchev, Peter, Schindeler, Aaron, Cunningham, Anthony L., Dehghani, Fariba
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955139/ https://www.ncbi.nlm.nih.gov/pubmed/35337158 http://dx.doi.org/10.3390/ph15030361

Ejemplares similares

Virtual screening and in vitro validation of natural compound inhibitors against SARS-CoV-2 spike protein
por: Power, Helen, et al.
Publicado: (2022)

Strategies for senolytic drug discovery
por: Power, Helen, et al.
Publicado: (2023)

The Effects of Thermal Pasteurisation, Freeze-Drying, and Gamma-Irradiation on the Antibacterial Properties of Donor Human Milk
por: Blackshaw, Katherine, et al.
Publicado: (2021)

Dynamic flow and shear stress as key parameters for intestinal cells morphology and polarization in an organ-on-a-chip model
por: Fois, Chiara A. M., et al.
Publicado: (2021)

Citrus Peel Flavonoids as Potential Cancer Prevention Agents
por: Koolaji, Nooshin, et al.
Publicado: (2020)

A benign process for the recovery of solanesol from tomato leaf waste
por: Arab, Marjan, et al.
Publicado: (2019)

Synthesis and Characterization of Bone Binding Antibiotic-1 (BBA-1), a Novel Antimicrobial for Orthopedic Applications
por: Kamble, Sumedh, et al.
Publicado: (2021)

A putative WAVE regulatory complex (WRC) interacting receptor sequence (WIRS) in the cytoplasmic tail of HSV-1 gE does not function in WRC recruitment or neuronal transport
por: Denes, Christopher E., et al.
Publicado: (2021)

Molecular docking analysis of a secondary metabolite with the glycoprotein receptors of HSV 1 and HSV 2
por: Saran, Natarajan, et al.
Publicado: (2019)

HSV-1 Glycoprotein D and Its Surface Receptors: Evaluation of Protein–Protein Interaction and Targeting by Triazole-Based Compounds through In Silico Approaches
por: Bivacqua, Roberta, et al.
Publicado: (2023)

Lipoprotein-induced cell growth and hemocyanin biosynthesis in rhogocytes
por: Sairi, Fareed, et al.
Publicado: (2022)

Medicinal plants and natural compounds against acyclovir-resistant HSV infections
por: Xu, Lin, et al.
Publicado: (2022)

Bisphosphonate-adsorbed ceramic nanoparticles increase bone formation in an injectable carrier for bone tissue engineering
por: Cheng, Tegan L, et al.
Publicado: (2015)

Subcellular Trafficking and Functional Relationship of the HSV-1 Glycoproteins N and M
por: Striebinger, Hannah, et al.
Publicado: (2016)

Herpes Simplex Virus Mistyping due to HSV-1 × HSV-2 Interspecies Recombination in Viral Gene Encoding Glycoprotein B
por: Casto, Amanda M., et al.
Publicado: (2020)

Molecular determinants of the interaction between HSV-1 glycoprotein D and heparan sulfate
por: Gandy, Lauren A., et al.
Publicado: (2022)

HSV‐1 Glycoproteins Are Delivered to Virus Assembly Sites Through Dynamin‐Dependent Endocytosis
por: Albecka, Anna, et al.
Publicado: (2015)

Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry Routes
por: Hilterbrand, Adam T., et al.
Publicado: (2021)

Interaction Mechanism Between the HSV-1 Glycoprotein B and the Antimicrobial Peptide Amyloid-β
por: Bourgade, Karine, et al.
Publicado: (2022)

Herpes Simplex Virus Type 1 Interactions with the Interferon System
por: Danastas, Kevin, et al.
Publicado: (2020)

Go go gadget glycoprotein!: HSV-1 draws on its sizeable glycoprotein tool kit to customize its diverse entry routes
por: Hilterbrand, Adam T., et al.
Publicado: (2019)

Induction of humoral responses to BHV-1 glycoprotein D expressed by HSV-1 amplicon vectors
por: Blanc, Andrea Maria, et al.
Publicado: (2012)

Screening of Natural Compounds as P-Glycoprotein Inhibitors against Multidrug Resistance
por: Marques, Sérgio M., et al.
Publicado: (2021)

Single dose of Glycoprotein K (gK)-deleted HSV-1 live-attenuated virus protects mice against lethal vaginal challenge with HSV-1 and HSV-2 and induces lasting T cell memory immune responses
por: Iyer, Arun V, et al.
Publicado: (2013)

HSV-1 0∆NLS vaccine elicits a robust B lymphocyte response and preserves vision without HSV-1 glycoprotein M or thymidine kinase recognition
por: Gmyrek, Grzegorz B., et al.
Publicado: (2022)

A Replication-Defective Herpes Simplex Virus (HSV)-2 Vaccine, HSV529, is Safe and Well-Tolerated in Adults with or without HSV Infection and Induces Significant HSV-2-Specific Antibody Responses in HSV Seronegative Individuals
por: Dropulic, Lesia, et al.
Publicado: (2017)

Helper T cells induced by an immunopurified herpes simplex virus type I (HSV-I) 115 kilodalton glycoprotein (gB) protect mice against HSV-I infection
Publicado: (1985)

A Single Intramuscular Vaccination of Mice with the HSV-1 VC2 Virus with Mutations in the Glycoprotein K and the Membrane Protein UL20 Confers Full Protection against Lethal Intravaginal Challenge with Virulent HSV-1 and HSV-2 Strains
por: Stanfield, Brent A., et al.
Publicado: (2014)

A Herpes Simplex Virus 2 (HSV-2) Glycoprotein D-expressing Nonreplicating Dominant-Negative HSV-2 Virus Vaccine Is Superior to a gD2 Subunit Vaccine against HSV-2 Genital Infection in Guinea Pigs
por: Zhang, Pengwei, et al.
Publicado: (2014)

Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic HSV as an intravesical therapy for superficial bladder cancer
por: Simpson, G R, et al.
Publicado: (2012)

Binding of HSV-1 Glycoprotein K (gK) to Signal Peptide Peptidase (SPP) Is Required for Virus Infectivity
por: Allen, Sariah J., et al.
Publicado: (2014)

Blocking HSV-1 glycoprotein K binding to signal peptide peptidase reduces virus infectivity in vitro and in vivo
por: Wang, Shaohui, et al.
Publicado: (2021)

Differential regulation of cytotoxicity pathway discriminating between HIV, HCV mono- and co-infection identified by transcriptome profiling of PBMCs
por: Wu, Jing Qin, et al.
Publicado: (2015)

Virtual Screening and Hit Selection of Natural Compounds as Acetylcholinesterase Inhibitors
por: Atanasova, Mariyana, et al.
Publicado: (2022)

Worldwide circulation of HSV-2 × HSV-1 recombinant strains
por: Koelle, David M., et al.
Publicado: (2017)

Cytoskeletons in the Closet—Subversion in Alphaherpesvirus Infections
por: Denes, Christopher E., et al.
Publicado: (2018)

Infection and Transport of Herpes Simplex Virus Type 1 in Neurons: Role of the Cytoskeleton
por: Miranda-Saksena, Monica, et al.
Publicado: (2018)

Viruses and neurodegeneration
por: Zhou, Li, et al.
Publicado: (2013)

Epigenetic Lens to Visualize the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Infection in COVID-19 Pandemic
por: Saksena, Nitin, et al.
Publicado: (2021)

HSV-2 glycoprotein gD targets the CC domain of tetherin and promotes tetherin degradation via lysosomal pathway
por: Liu, Yalan, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_3l0i8t509o14js17r7odg59ekl