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Outcomes of Nonagenarians with Acute Myocardial Infarction with or without Coronary Intervention

Percutaneous coronary intervention (PCI) is the mainstay treatment of acute myocardial infarction (AMI); however, many clinicians are reluctant to perform PCI in the elderly population. This study aimed to compare the clinical outcomes of PCI versus medical therapy in nonagenarian Korean patients wi...

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Autores principales: Oh, Seok, Jeong, Myung Ho, Cho, Kyung Hoon, Kim, Min Chul, Sim, Doo Sun, Hong, Young Joon, Kim, Ju Han, Ahn, Youngkeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955178/
https://www.ncbi.nlm.nih.gov/pubmed/35329920
http://dx.doi.org/10.3390/jcm11061593
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author Oh, Seok
Jeong, Myung Ho
Cho, Kyung Hoon
Kim, Min Chul
Sim, Doo Sun
Hong, Young Joon
Kim, Ju Han
Ahn, Youngkeun
author_facet Oh, Seok
Jeong, Myung Ho
Cho, Kyung Hoon
Kim, Min Chul
Sim, Doo Sun
Hong, Young Joon
Kim, Ju Han
Ahn, Youngkeun
author_sort Oh, Seok
collection PubMed
description Percutaneous coronary intervention (PCI) is the mainstay treatment of acute myocardial infarction (AMI); however, many clinicians are reluctant to perform PCI in the elderly population. This study aimed to compare the clinical outcomes of PCI versus medical therapy in nonagenarian Korean patients with AMI. We compared the clinical outcomes of nonagenarian patients with AMI with or without PCI. From the pooled data, based on a series of Korean AMI registries during 2005–2020, 467 consecutive patients were selected and categorized into two groups: the PCI and no-PCI groups. The primary endpoint was 1-year major adverse cardiac event (MACE), a composite of all-cause death, non-fatal myocardial infarction, and any revascularization. Among the 467 participants, 68.5% received PCI. The PCI group had lower proportions of Killip classes III-IV, previous heart failure, and left ventricular ejection fraction <40%, but had higher proportions of all prescribed medications and STEMI diagnosis. The 1-year MACE and all-cause death were higher in the no-PCI group, although partially attenuated post-IPTW. Our study showed that nonagenarian patients with AMI undergoing PCI had better clinical outcomes than those without PCI. Nonetheless, further investigation is needed in the future to elucidate whether PCI is beneficial for this population.
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spelling pubmed-89551782022-03-26 Outcomes of Nonagenarians with Acute Myocardial Infarction with or without Coronary Intervention Oh, Seok Jeong, Myung Ho Cho, Kyung Hoon Kim, Min Chul Sim, Doo Sun Hong, Young Joon Kim, Ju Han Ahn, Youngkeun J Clin Med Article Percutaneous coronary intervention (PCI) is the mainstay treatment of acute myocardial infarction (AMI); however, many clinicians are reluctant to perform PCI in the elderly population. This study aimed to compare the clinical outcomes of PCI versus medical therapy in nonagenarian Korean patients with AMI. We compared the clinical outcomes of nonagenarian patients with AMI with or without PCI. From the pooled data, based on a series of Korean AMI registries during 2005–2020, 467 consecutive patients were selected and categorized into two groups: the PCI and no-PCI groups. The primary endpoint was 1-year major adverse cardiac event (MACE), a composite of all-cause death, non-fatal myocardial infarction, and any revascularization. Among the 467 participants, 68.5% received PCI. The PCI group had lower proportions of Killip classes III-IV, previous heart failure, and left ventricular ejection fraction <40%, but had higher proportions of all prescribed medications and STEMI diagnosis. The 1-year MACE and all-cause death were higher in the no-PCI group, although partially attenuated post-IPTW. Our study showed that nonagenarian patients with AMI undergoing PCI had better clinical outcomes than those without PCI. Nonetheless, further investigation is needed in the future to elucidate whether PCI is beneficial for this population. MDPI 2022-03-14 /pmc/articles/PMC8955178/ /pubmed/35329920 http://dx.doi.org/10.3390/jcm11061593 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Oh, Seok
Jeong, Myung Ho
Cho, Kyung Hoon
Kim, Min Chul
Sim, Doo Sun
Hong, Young Joon
Kim, Ju Han
Ahn, Youngkeun
Outcomes of Nonagenarians with Acute Myocardial Infarction with or without Coronary Intervention
title Outcomes of Nonagenarians with Acute Myocardial Infarction with or without Coronary Intervention
title_full Outcomes of Nonagenarians with Acute Myocardial Infarction with or without Coronary Intervention
title_fullStr Outcomes of Nonagenarians with Acute Myocardial Infarction with or without Coronary Intervention
title_full_unstemmed Outcomes of Nonagenarians with Acute Myocardial Infarction with or without Coronary Intervention
title_short Outcomes of Nonagenarians with Acute Myocardial Infarction with or without Coronary Intervention
title_sort outcomes of nonagenarians with acute myocardial infarction with or without coronary intervention
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955178/
https://www.ncbi.nlm.nih.gov/pubmed/35329920
http://dx.doi.org/10.3390/jcm11061593
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