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Nutrient Intake with Early Progressive Enteral Feeding and Growth of Very Low-Birth-Weight Newborns

Early nutrition is one of the most modifiable factors influencing postnatal growth. Optimal nutrient intakes for very preterm infants remain unknown, and poor postnatal growth is common in this population. The aim of this study was to assess nutrient intake during the first 4 weeks of life with earl...

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Autores principales: Brinkis, Rasa, Albertsson-Wikland, Kerstin, Tamelienė, Rasa, Vinskaitė, Asta, Šmigelskas, Kastytis, Verkauskienė, Rasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955398/
https://www.ncbi.nlm.nih.gov/pubmed/35334838
http://dx.doi.org/10.3390/nu14061181
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author Brinkis, Rasa
Albertsson-Wikland, Kerstin
Tamelienė, Rasa
Vinskaitė, Asta
Šmigelskas, Kastytis
Verkauskienė, Rasa
author_facet Brinkis, Rasa
Albertsson-Wikland, Kerstin
Tamelienė, Rasa
Vinskaitė, Asta
Šmigelskas, Kastytis
Verkauskienė, Rasa
author_sort Brinkis, Rasa
collection PubMed
description Early nutrition is one of the most modifiable factors influencing postnatal growth. Optimal nutrient intakes for very preterm infants remain unknown, and poor postnatal growth is common in this population. The aim of this study was to assess nutrient intake during the first 4 weeks of life with early progressive enteral feeding and its impact on the in-hospital growth of very low-birth-weight (VLBW) infants. In total, 120 infants with birth weights below 1500 g and gestational ages below 35 weeks were included in the study. Nutrient intakes were assessed daily for the first 28 days. Growth was measured weekly until discharge. Median time of parenteral nutrition support was 6 days. Target enteral nutrient and energy intake were reached at day 10 of life, and remained stable until day 28, with slowly declining protein intake. Median z-scores at discharge were −0.73, −0.49, and −0.31 for weight, length, and head circumference, respectively. Extrauterine growth restriction was observed in 30.3% of the whole cohort. Protein, carbohydrates, and energy intakes correlated positively with weight gain and head circumference growth. Early progressive enteral feeding with human milk is well tolerated in VLBW infants. Target enteral nutrient intake may be reached early and improve in-hospital growth.
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spelling pubmed-89553982022-03-26 Nutrient Intake with Early Progressive Enteral Feeding and Growth of Very Low-Birth-Weight Newborns Brinkis, Rasa Albertsson-Wikland, Kerstin Tamelienė, Rasa Vinskaitė, Asta Šmigelskas, Kastytis Verkauskienė, Rasa Nutrients Article Early nutrition is one of the most modifiable factors influencing postnatal growth. Optimal nutrient intakes for very preterm infants remain unknown, and poor postnatal growth is common in this population. The aim of this study was to assess nutrient intake during the first 4 weeks of life with early progressive enteral feeding and its impact on the in-hospital growth of very low-birth-weight (VLBW) infants. In total, 120 infants with birth weights below 1500 g and gestational ages below 35 weeks were included in the study. Nutrient intakes were assessed daily for the first 28 days. Growth was measured weekly until discharge. Median time of parenteral nutrition support was 6 days. Target enteral nutrient and energy intake were reached at day 10 of life, and remained stable until day 28, with slowly declining protein intake. Median z-scores at discharge were −0.73, −0.49, and −0.31 for weight, length, and head circumference, respectively. Extrauterine growth restriction was observed in 30.3% of the whole cohort. Protein, carbohydrates, and energy intakes correlated positively with weight gain and head circumference growth. Early progressive enteral feeding with human milk is well tolerated in VLBW infants. Target enteral nutrient intake may be reached early and improve in-hospital growth. MDPI 2022-03-11 /pmc/articles/PMC8955398/ /pubmed/35334838 http://dx.doi.org/10.3390/nu14061181 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Brinkis, Rasa
Albertsson-Wikland, Kerstin
Tamelienė, Rasa
Vinskaitė, Asta
Šmigelskas, Kastytis
Verkauskienė, Rasa
Nutrient Intake with Early Progressive Enteral Feeding and Growth of Very Low-Birth-Weight Newborns
title Nutrient Intake with Early Progressive Enteral Feeding and Growth of Very Low-Birth-Weight Newborns
title_full Nutrient Intake with Early Progressive Enteral Feeding and Growth of Very Low-Birth-Weight Newborns
title_fullStr Nutrient Intake with Early Progressive Enteral Feeding and Growth of Very Low-Birth-Weight Newborns
title_full_unstemmed Nutrient Intake with Early Progressive Enteral Feeding and Growth of Very Low-Birth-Weight Newborns
title_short Nutrient Intake with Early Progressive Enteral Feeding and Growth of Very Low-Birth-Weight Newborns
title_sort nutrient intake with early progressive enteral feeding and growth of very low-birth-weight newborns
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955398/
https://www.ncbi.nlm.nih.gov/pubmed/35334838
http://dx.doi.org/10.3390/nu14061181
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