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The Deployment of a Newly Developed Proximal Release-Type Colonic Stent Is Feasible for Malignant Colorectal Obstruction near the Anal Verge: A Single-Center Preliminary Study

Introduction: Colonic self-expandable metallic stents are widely used to treat malignant colorectal obstructions. Stent placement in lesions near the dentate line causes problems, including severe pain due to difficulty in positioning the stent accurately. Therefore, a proximal release-type stent wa...

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Autores principales: Wada, Kaoru, Kuwai, Toshio, Sugata, Syuhei, Hamada, Takuro, Moriuchi, Riho, Tamaru, Yuzuru, Kusunoki, Ryusaku, Yamaguchi, Atsushi, Kouno, Hirotaka, Ishaq, Sauid, Kohno, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955481/
https://www.ncbi.nlm.nih.gov/pubmed/35330000
http://dx.doi.org/10.3390/jcm11061675
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author Wada, Kaoru
Kuwai, Toshio
Sugata, Syuhei
Hamada, Takuro
Moriuchi, Riho
Tamaru, Yuzuru
Kusunoki, Ryusaku
Yamaguchi, Atsushi
Kouno, Hirotaka
Ishaq, Sauid
Kohno, Hiroshi
author_facet Wada, Kaoru
Kuwai, Toshio
Sugata, Syuhei
Hamada, Takuro
Moriuchi, Riho
Tamaru, Yuzuru
Kusunoki, Ryusaku
Yamaguchi, Atsushi
Kouno, Hirotaka
Ishaq, Sauid
Kohno, Hiroshi
author_sort Wada, Kaoru
collection PubMed
description Introduction: Colonic self-expandable metallic stents are widely used to treat malignant colorectal obstructions. Stent placement in lesions near the dentate line causes problems, including severe pain due to difficulty in positioning the stent accurately. Therefore, a proximal release-type stent was developed to overcome this issue, and this preliminary study aimed to investigate its efficacy and safety. Patients and Methods: This research enrolled eight patients with malignant colorectal obstructions up to 10 cm from the anal verge who required placement of the newly developed proximal release-type colonic stent. The primary outcome was the clinical success rate, and the secondary outcomes were the technical success and adverse events rates. Results: The technical and clinical success rates were 87.5% each, and the mean procedure time was 25.5 ± 22.0 min. The mean procedure time in the rectosigmoid colon was significantly longer than that in the rectum. Only one (12.5%) patient had stent migration, and neither anal pain nor tenesmus was observed. Discussion: The stent was highly effective in treating lesions near the anal verge, and it might contribute to the expansion of indications for colorectal stents for lesions near the dentate line. However, the indications for rectosigmoid colon lesions should be cautiously considered.
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spelling pubmed-89554812022-03-26 The Deployment of a Newly Developed Proximal Release-Type Colonic Stent Is Feasible for Malignant Colorectal Obstruction near the Anal Verge: A Single-Center Preliminary Study Wada, Kaoru Kuwai, Toshio Sugata, Syuhei Hamada, Takuro Moriuchi, Riho Tamaru, Yuzuru Kusunoki, Ryusaku Yamaguchi, Atsushi Kouno, Hirotaka Ishaq, Sauid Kohno, Hiroshi J Clin Med Article Introduction: Colonic self-expandable metallic stents are widely used to treat malignant colorectal obstructions. Stent placement in lesions near the dentate line causes problems, including severe pain due to difficulty in positioning the stent accurately. Therefore, a proximal release-type stent was developed to overcome this issue, and this preliminary study aimed to investigate its efficacy and safety. Patients and Methods: This research enrolled eight patients with malignant colorectal obstructions up to 10 cm from the anal verge who required placement of the newly developed proximal release-type colonic stent. The primary outcome was the clinical success rate, and the secondary outcomes were the technical success and adverse events rates. Results: The technical and clinical success rates were 87.5% each, and the mean procedure time was 25.5 ± 22.0 min. The mean procedure time in the rectosigmoid colon was significantly longer than that in the rectum. Only one (12.5%) patient had stent migration, and neither anal pain nor tenesmus was observed. Discussion: The stent was highly effective in treating lesions near the anal verge, and it might contribute to the expansion of indications for colorectal stents for lesions near the dentate line. However, the indications for rectosigmoid colon lesions should be cautiously considered. MDPI 2022-03-17 /pmc/articles/PMC8955481/ /pubmed/35330000 http://dx.doi.org/10.3390/jcm11061675 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wada, Kaoru
Kuwai, Toshio
Sugata, Syuhei
Hamada, Takuro
Moriuchi, Riho
Tamaru, Yuzuru
Kusunoki, Ryusaku
Yamaguchi, Atsushi
Kouno, Hirotaka
Ishaq, Sauid
Kohno, Hiroshi
The Deployment of a Newly Developed Proximal Release-Type Colonic Stent Is Feasible for Malignant Colorectal Obstruction near the Anal Verge: A Single-Center Preliminary Study
title The Deployment of a Newly Developed Proximal Release-Type Colonic Stent Is Feasible for Malignant Colorectal Obstruction near the Anal Verge: A Single-Center Preliminary Study
title_full The Deployment of a Newly Developed Proximal Release-Type Colonic Stent Is Feasible for Malignant Colorectal Obstruction near the Anal Verge: A Single-Center Preliminary Study
title_fullStr The Deployment of a Newly Developed Proximal Release-Type Colonic Stent Is Feasible for Malignant Colorectal Obstruction near the Anal Verge: A Single-Center Preliminary Study
title_full_unstemmed The Deployment of a Newly Developed Proximal Release-Type Colonic Stent Is Feasible for Malignant Colorectal Obstruction near the Anal Verge: A Single-Center Preliminary Study
title_short The Deployment of a Newly Developed Proximal Release-Type Colonic Stent Is Feasible for Malignant Colorectal Obstruction near the Anal Verge: A Single-Center Preliminary Study
title_sort deployment of a newly developed proximal release-type colonic stent is feasible for malignant colorectal obstruction near the anal verge: a single-center preliminary study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955481/
https://www.ncbi.nlm.nih.gov/pubmed/35330000
http://dx.doi.org/10.3390/jcm11061675
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