Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report

Mounting evidence indicates that new arrhythmic events frequently occur during and after coronavirus disease (COVID-19), posing additional mortality risk in older-aged and critically ill patients. However, the underlying mechanisms and cardio pathological substrates of COVID-related arrhythmias have...

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Detalles Bibliográficos
Autores principales: Jakovac, Hrvoje, Ferenčić, Antun, Stemberger, Christophe, Mohar Vitezić, Bojana, Cuculić, Dražen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955572/
https://www.ncbi.nlm.nih.gov/pubmed/35324590
http://dx.doi.org/10.3390/tropicalmed7030043
Descripción
Sumario:Mounting evidence indicates that new arrhythmic events frequently occur during and after coronavirus disease (COVID-19), posing additional mortality risk in older-aged and critically ill patients. However, the underlying mechanisms and cardio pathological substrates of COVID-related arrhythmias have not been clarified yet. Here, we report findings of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens and genes in the atrioventricular node (AV-node) of a cardiac conduction system, pointing to its direct infection as a possible arrhythmogenic factor.

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