Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report

Mounting evidence indicates that new arrhythmic events frequently occur during and after coronavirus disease (COVID-19), posing additional mortality risk in older-aged and critically ill patients. However, the underlying mechanisms and cardio pathological substrates of COVID-related arrhythmias have...

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Autores principales: Jakovac, Hrvoje, Ferenčić, Antun, Stemberger, Christophe, Mohar Vitezić, Bojana, Cuculić, Dražen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955572/
https://www.ncbi.nlm.nih.gov/pubmed/35324590
http://dx.doi.org/10.3390/tropicalmed7030043
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author Jakovac, Hrvoje
Ferenčić, Antun
Stemberger, Christophe
Mohar Vitezić, Bojana
Cuculić, Dražen
author_facet Jakovac, Hrvoje
Ferenčić, Antun
Stemberger, Christophe
Mohar Vitezić, Bojana
Cuculić, Dražen
author_sort Jakovac, Hrvoje
collection PubMed
description Mounting evidence indicates that new arrhythmic events frequently occur during and after coronavirus disease (COVID-19), posing additional mortality risk in older-aged and critically ill patients. However, the underlying mechanisms and cardio pathological substrates of COVID-related arrhythmias have not been clarified yet. Here, we report findings of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens and genes in the atrioventricular node (AV-node) of a cardiac conduction system, pointing to its direct infection as a possible arrhythmogenic factor.
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spelling pubmed-89555722022-03-26 Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report Jakovac, Hrvoje Ferenčić, Antun Stemberger, Christophe Mohar Vitezić, Bojana Cuculić, Dražen Trop Med Infect Dis Case Report Mounting evidence indicates that new arrhythmic events frequently occur during and after coronavirus disease (COVID-19), posing additional mortality risk in older-aged and critically ill patients. However, the underlying mechanisms and cardio pathological substrates of COVID-related arrhythmias have not been clarified yet. Here, we report findings of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens and genes in the atrioventricular node (AV-node) of a cardiac conduction system, pointing to its direct infection as a possible arrhythmogenic factor. MDPI 2022-03-04 /pmc/articles/PMC8955572/ /pubmed/35324590 http://dx.doi.org/10.3390/tropicalmed7030043 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Jakovac, Hrvoje
Ferenčić, Antun
Stemberger, Christophe
Mohar Vitezić, Bojana
Cuculić, Dražen
Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report
title Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report
title_full Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report
title_fullStr Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report
title_full_unstemmed Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report
title_short Detection of SARS-CoV-2 Antigens in the AV-Node of a Cardiac Conduction System—A Case Report
title_sort detection of sars-cov-2 antigens in the av-node of a cardiac conduction system—a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955572/
https://www.ncbi.nlm.nih.gov/pubmed/35324590
http://dx.doi.org/10.3390/tropicalmed7030043
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