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A New Insight into Toxicity of Colchicine Analogues by Molecular Docking Analysis Based on Intestinal Tight Junction Protein ZO-1

Colchicine (COL) is a well-known plant alkaloid long used for medical purposes due to the selective anti-inflammatory effect on acute gouty arthritis. It is also a kind of mitosis toxin with strong inhibitory effects of cell division and is therefore being applied to the treatment of various cancers...

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Detalles Bibliográficos
Autores principales: Liu, Jiali, Gao, Rongrong, Gu, Xuejing, Yu, Bin, Wu, Yan, Li, Qiushi, Xiang, Ping, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955668/
https://www.ncbi.nlm.nih.gov/pubmed/35335160
http://dx.doi.org/10.3390/molecules27061797