Cargando…

Lycorine Ameliorates Thioacetamide-Induced Hepatic Fibrosis in Rats: Emphasis on Antioxidant, Anti-Inflammatory, and STAT3 Inhibition Effects

Liver fibrosis is a foremost medical concern worldwide. In Saudi Arabia, numerous risk factors contribute to its high rates. Lycorine—a natural alkaloid—has antioxidant, anti-inflammatory, and antitumor activates. It has been reported to inhibit STAT3 in cancer. Therefore, this study aimed at invest...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alkreathy, Huda Mohammed, Esmat, Ahmed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955817/ https://www.ncbi.nlm.nih.gov/pubmed/35337166 http://dx.doi.org/10.3390/ph15030369

Ejemplares similares

Tetramethylpyrazine ameliorates indomethacin-induced gastric ulcer in rats: Impact on oxidative, inflammatory, and angiogenic machineries
por: AlKreathy, Huda M., et al.
Publicado: (2020)

Thioacetamide-induced hepatic fibrosis in the common marmoset
por: Inoue, Takashi, et al.
Publicado: (2018)

Anti-Fibrotic Efficacy of Apigenin in a Mice Model of Carbon Tetrachloride-Induced Hepatic Fibrosis by Modulation of Oxidative Stress, Inflammation, and Fibrogenesis: A Preclinical Study
por: Melaibari, Maryam, et al.
Publicado: (2023)

Ameliorative Effect of Curcumin-Encapsulated Hyaluronic Acid–PLA Nanoparticles on Thioacetamide-Induced Murine Hepatic Fibrosis
por: Chen, Yu-Nong, et al.
Publicado: (2016)

Dendropanax morbifera Ameliorates Thioacetamide-Induced Hepatic Fibrosis via TGF-β1/Smads Pathways
por: Yang, Hun Yong, et al.
Publicado: (2019)

Lycorine ameliorates isoproterenol-induced cardiac dysfunction mainly via inhibiting inflammation, fibrosis, oxidative stress and apoptosis
por: Wu, Ji, et al.
Publicado: (2021)

Transforming Growth Factor β Neutralization Ameliorates Pre-Existing Hepatic Fibrosis and Reduces Cholangiocarcinoma in Thioacetamide-Treated Rats
por: Ling, Hong, et al.
Publicado: (2013)

Dunaliella salina microalgae oppose thioacetamide-induced hepatic fibrosis in rats
por: El-Baz, Farouk K., et al.
Publicado: (2019)

Lycorine Displays Potent Antitumor Efficacy in Colon Carcinoma by Targeting STAT3
por: Wu, Song, et al.
Publicado: (2018)

Estrogen Deficiency Potentiates Thioacetamide-Induced Hepatic Fibrosis in Sprague-Dawley Rats
por: Lee, Yong Hee, et al.
Publicado: (2019)

Vitamin D Ameliorates the Hepatic Oxidative Damage and Fibrotic Effect Caused by Thioacetamide in Rats
por: Megahed, Aya, et al.
Publicado: (2023)

Urolithin A’s Antioxidative, Anti-Inflammatory, and Antiapoptotic Activities Mitigate Doxorubicin-Induced Liver Injury in Wistar Rats
por: Karim, Shahid, et al.
Publicado: (2023)

Anti-hepatofibrosis effect of Allium senescens in activated hepatic stellate cells and thioacetamide-induced fibrosis rat model
por: Shin, Gwang-Mo, et al.
Publicado: (2018)

Benzoindolizidine Alkaloids Tylophorine and Lycorine and Their Analogues with Antiviral, Anti-Inflammatory, and Anticancer Properties: Promises and Challenges
por: Di Sotto, Antonella, et al.
Publicado: (2023)

In Vitro Inhibition of Alphaviruses by Lycorine
por: Li, Na, et al.
Publicado: (2021)

Anti-fibrotic effects of Orostachys japonicus A. Berger (Crassulaceae) on hepatic stellate cells and thioacetamide-induced fibrosis in rats
por: Koppula, Sushruta, et al.
Publicado: (2017)

Solanum trilobatum L. Ameliorate Thioacetamide-Induced Oxidative Stress and Hepatic Damage in Albino Rats
por: Ganesan, Kumar, et al.
Publicado: (2017)

Amelioration of thioacetamide-induced liver toxicity in Wistar rats by rutin
por: Zargar, Seema, et al.
Publicado: (2017)

Thioredoxin prevents thioacetamide-induced acute hepatitis
por: Okuyama, Hiroaki, et al.
Publicado: (2004)

Effects of FGF21‐secreting adipose‐derived stem cells in thioacetamide‐induced hepatic fibrosis
por: Kang, Hwansu, et al.
Publicado: (2018)

Chemoprotective effect of omega-3 fatty acids on thioacetamide induced hepatic fibrosis in male rats
por: Al-Attar, Atef M., et al.
Publicado: (2017)

Antihyperglycemic Potential of Grewia asiatica Fruit Extract against Streptozotocin-Induced Hyperglycemia in Rats: Anti-Inflammatory and Antioxidant Mechanisms
por: Khattab, Hala A. H., et al.
Publicado: (2015)

Ferroptosis is involved in the anti-tumor effect of lycorine in renal cell carcinoma cells
por: Du, Yang, et al.
Publicado: (2021)

Haematococcus pluvialis Carotenoids Enrich Fractions Ameliorate Liver Fibrosis Induced by Thioacetamide in Rats: Modulation of Metalloproteinase and Its Inhibitor
por: El-Baz, Farouk K., et al.
Publicado: (2021)

Gastrodia elata rhizoma ameliorates thioacetamide-induced liver injury in dogs
por: Yoon, Hye-Bin, et al.
Publicado: (2023)

Antifibrotic effects of crocin on thioacetamide-induced liver fibrosis in mice
por: Algandaby, Mardi M.
Publicado: (2018)

Novel liver fibrosis model in Macaca fascicularis induced by thioacetamide
por: Matsuo, Megumi, et al.
Publicado: (2020)

The ameliorating role of sofosbuvir and daclatasvir on thioacetamide-induced kidney injury in adult albino rats
por: Moustafa, Ahmed H., et al.
Publicado: (2023)

Multiple biological functions and pharmacological effects of lycorine
por: Cao, ZhiFei, et al.
Publicado: (2013)

Lycorine inhibits angiogenesis by docking to PDGFRα
por: Lv, Fei, et al.
Publicado: (2022)

Sinapic Acid Attenuate Liver Injury by Modulating Antioxidant Activity and Inflammatory Cytokines in Thioacetamide-Induced Liver Cirrhosis in Rats
por: Jabbar, Ahmed A. J., et al.
Publicado: (2023)

Regression of fibrosis by cilostazol in a rat model of thioacetamide-induced liver fibrosis: Up regulation of hepatic cAMP, and modulation of inflammatory, oxidative stress and apoptotic biomarkers
por: El Awdan, Sally A., et al.
Publicado: (2019)

A standardized pomegranate fruit extract ameliorates thioacetamide-induced liver fibrosis in rats via AGE-RAGE-ROS signaling
por: Abouelezz, Hadeer M., et al.
Publicado: (2023)

Protection of rats from thioacetamide-induced hepatic fibrosis by the extracts of a traditional Uighur medicine Cichorium glandulosum
por: Qin, Dongmei, et al.
Publicado: (2014)

Dendropanoxide Alleviates Thioacetamide-induced Hepatic Fibrosis via Inhibition of ROS Production and Inflammation in BALB/(C) Mice
por: Kundu, Amit, et al.
Publicado: (2023)

Model of Liver Fibrosis Induction by Thioacetamide in Rats for Regenerative Therapy Studies
por: Enciso, Nathaly, et al.
Publicado: (2022)

Lycorine Hydrochloride Inhibits the Virulence Traits of Candida albicans
por: Yang, Longfei, et al.
Publicado: (2019)

Non-invasive index of liver fibrosis induced by alcohol, thioacetamide and schistosomal infection in mice
por: Hessien, Mohamed H, et al.
Publicado: (2010)

Co-Treatments of Gardeniae Fructus and Silymarin Ameliorates Excessive Oxidative Stress-Driven Liver Fibrosis by Regulation of Hepatic Sirtuin1 Activities Using Thioacetamide-Induced Mice Model
por: Lee, Jin A, et al.
Publicado: (2022)

Ameliorative Potential of Donepezil with or without Prednisolone in Bleomycin-Induced Pulmonary Fibrosis in Rats: Involvement of the Anti-Inflammatory, Antioxidant, and the Antifibrotic Pathways
por: Mina, Shery, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_32b5ekuruuepm22lg8semphuqf