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Shikonin Derivatives Inhibit Inflammation Processes and Modulate MAPK Signaling in Human Healthy and Osteoarthritis Chondrocytes

Osteoarthritis (OA) is the most common joint disorder and is characterized by the degeneration of articular cartilage. To develop new therapeutic approaches, we investigated the effect of shikonin derivatives on inflammation, MMP expression, and the regulation of MAPK signaling in human healthy (HC)...

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Detalles Bibliográficos
Autores principales:	Lohberger, Birgit, Kaltenegger, Heike, Eck, Nicole, Glänzer, Dietmar, Sadoghi, Patrick, Leithner, Andreas, Bauer, Rudolf, Kretschmer, Nadine, Steinecker-Frohnwieser, Bibiane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955849/ https://www.ncbi.nlm.nih.gov/pubmed/35328817 http://dx.doi.org/10.3390/ijms23063396

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