Pyrazolo[4,3-c]pyridine Sulfonamides as Carbonic Anhydrase Inhibitors: Synthesis, Biological and In Silico Studies

Carbonic anhydrases (CAs, EC 4.2.1.1) catalyze the essential reaction of CO(2) hydration in all living organisms, being actively involved in the regulation of a plethora of patho-/physiological conditions. A series of chromene-based sulfonamides were synthesized and tested as possible CA inhibitors....

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Detalles Bibliográficos
Autores principales: Angeli, Andrea, Kartsev, Victor, Petrou, Anthi, Lichitsky, Boris, Komogortsev, Andrey, Pinteala, Mariana, Geronikaki, Athina, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955975/
https://www.ncbi.nlm.nih.gov/pubmed/35337114
http://dx.doi.org/10.3390/ph15030316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955975/
https://www.ncbi.nlm.nih.gov/pubmed/35337114
http://dx.doi.org/10.3390/ph15030316

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