Mechanical-Stress-Related Epigenetic Regulation of ZIC1 Transcription Factor in the Etiology of Postmenopausal Osteoporosis

Mechanical loading exerts a profound influence on bone density and architecture, but the exact mechanism is unknown. Our study shows that expression of the neurological transcriptional factor zinc finger of the cerebellum 1 (ZIC1) is markedly increased in trabecular bone biopsies in the lumbar spine...

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Detalles Bibliográficos
Autores principales: Datta, Harish K., Kringen, Marianne K., Tuck, Stephen P., Salpingidou, Georgia, Olstad, Ole K., Gautvik, Kaare M., Cockell, Simon J., Gautvik, Vigdis T., Prediger, Michael, Wu, Jun Jie, Birch, Mark A., Reppe, Sjur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955993/
https://www.ncbi.nlm.nih.gov/pubmed/35328378
http://dx.doi.org/10.3390/ijms23062957

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