Cargando…

Unraveling the Complexity of the Rhomboid Serine Protease 4 Family of Babesia bovis Using Bioinformatics and Experimental Studies

Babesia bovis, a tick-transmitted apicomplexan protozoon, infects cattle in tropical and subtropical regions around the world. In the apicomplexans Toxoplasma gondii and Plasmodium falciparum, rhomboid serine protease 4 (ROM4) fulfills an essential role in host cell invasion. We thus investigated B....

Descripción completa

Detalles Bibliográficos
Autores principales:	Gallenti, Romina, Hussein, Hala E., Alzan, Heba F., Suarez, Carlos E., Ueti, Massaro, Asurmendi, Sebastián, Benitez, Daniel, Araujo, Flabio R., Rolls, Peter, Sibeko-Matjila, Kgomotso, Schnittger, Leonhard, Florin-Christensen, Mónica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956091/ https://www.ncbi.nlm.nih.gov/pubmed/35335668 http://dx.doi.org/10.3390/pathogens11030344

Ejemplares similares

Comparative Degradome Analysis of the Bovine Piroplasmid Pathogens Babesia bovis and Theileria annulata
por: Poklepovich, Tomás Javier, et al.
Publicado: (2023)

Assessment of Babesia bovis 6cys A and 6cys B as components of transmission blocking vaccines for babesiosis
por: Alzan, Heba F., et al.
Publicado: (2021)

Expression of 6-Cys Gene Superfamily Defines Babesia bovis Sexual Stage Development within Rhipicephalus microplus
por: Alzan, Heba F., et al.
Publicado: (2016)

Identification of novel immune correlates of protection against acute bovine babesiosis by superinfecting cattle with in vitro culture attenuated and virulent Babesia bovis strains
por: Bastos, Reginaldo G., et al.
Publicado: (2022)

A Culture-Adapted Strain of Babesia bovis Has Reduced Subpopulation Complexity and Is Unable to Complete Its Natural Life Cycle in Ticks
por: Alzan, Heba F., et al.
Publicado: (2022)

The Babesia bovis hap2 gene is not required for blood stage replication, but expressed upon in vitro sexual stage induction
por: Hussein, Hala E., et al.
Publicado: (2017)

Comparative Bioinformatics Analysis of Transcription Factor Genes Indicates Conservation of Key Regulatory Domains among Babesia bovis, Babesia microti, and Theileria equi
por: Alzan, Heba F., et al.
Publicado: (2016)

Differential Expression of Three Members of the Multidomain Adhesion CCp Family in Babesia bigemina, Babesia bovis and Theileria equi
por: Bastos, Reginaldo G., et al.
Publicado: (2013)

Establishment of Babesia bovis In Vitro Culture Using Medium Free of Animal Products
por: Álvarez Martínez, Jesús A., et al.
Publicado: (2021)

Bovipain-2, the falcipain-2 ortholog, is expressed in intraerythrocytic stages of the tick-transmitted hemoparasite Babesia bovis
por: Mesplet, María, et al.
Publicado: (2010)

Silencing expression of the Rhipicephalus microplus vitellogenin receptor gene blocks Babesia bovis transmission and interferes with oocyte maturation
por: Hussein, Hala E., et al.
Publicado: (2019)

Genome-wide analysis of peptidase content and expression in a virulent and attenuated Babesia bovis strain pair
por: Mesplet, Maria, et al.
Publicado: (2011)

Differential paired stage-specific expression of Babesia bovis cysteine-rich GCC2/GCC3 domain family proteins (BboGDP) during development within Rhipicephalus microplus
por: Hussein, Hala E., et al.
Publicado: (2023)

A Virulent Babesia bovis Strain Failed to Infect White-Tailed Deer (Odocoileus virginianus)
por: Ueti, Massaro W., et al.
Publicado: (2015)

Babesia microti Immunoreactive Rhoptry-Associated Protein-1 Paralogs Are Ancestral Members of the Piroplasmid-Confined RAP-1 Family
por: Bastos, Reginaldo G., et al.
Publicado: (2021)

Identification of CCp5 and FNPA as Novel Non-canonical Members of the CCp Protein Family in Babesia bovis
por: Ozubek, Sezayi, et al.
Publicado: (2022)

Geno- and phenotypic characteristics of a transfected Babesia bovis 6-Cys-E knockout clonal line
por: Alzan, Heba F., et al.
Publicado: (2017)

Reclassification of Theileria annae as Babesia vulpes sp. nov.
por: Baneth, Gad, et al.
Publicado: (2015)

Differential expression of calcium-dependent protein kinase 4, tubulin tyrosine ligase, and methyltransferase by xanthurenic acid-induced Babesia bovis sexual stages
por: Hussein, Hala E., et al.
Publicado: (2021)

A Transfected Babesia bovis Parasite Line Expressing eGFP Is Able to Complete the Full Life Cycle of the Parasite in Mammalian and Tick Hosts
por: Johnson, Wendell C., et al.
Publicado: (2022)

Comparison of high throughput RNA sequences between Babesia bigemina and Babesia bovis revealed consistent differential gene expression that is required for the Babesia life cycle in the vertebrate and invertebrate hosts
por: Capelli-Peixoto, Janaina, et al.
Publicado: (2022)

Spherical Body Protein 2 truncated copy 11 as a specific Babesia bovis attenuation marker
por: Gallego-Lopez, Gina M., et al.
Publicado: (2018)

Transcriptome dataset of Babesia bovis life stages within vertebrate and invertebrate hosts
por: Ueti, Massaro W., et al.
Publicado: (2020)

The Rhipicephalus (Boophilus) microplus Bm86 gene plays a critical role in the fitness of ticks fed on cattle during acute Babesia bovis infection
por: Bastos, Reginaldo G, et al.
Publicado: (2010)

Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny
por: Bastos, Reginaldo G, et al.
Publicado: (2009)

Vaccination with an in vitro culture attenuated Babesia bovis strain safely protects highly susceptible adult cattle against acute bovine babesiosis
por: Bastos, Reginaldo G., et al.
Publicado: (2023)

Thrombospondin-Related Anonymous Protein (TRAP) Family Expression by Babesia bovis Life Stages within the Mammalian Host and Tick Vector
por: Masterson, Hayley E., et al.
Publicado: (2022)

Vaccination of cattle with the Babesia bovis sexual-stage protein HAP2 abrogates parasite transmission by Rhipicephalus microplus ticks
por: Silva, Marta G., et al.
Publicado: (2023)

In Silico Survey and Characterization of Babesia microti Functional and Non-Functional Proteases
por: Florin-Christensen, Monica, et al.
Publicado: (2021)

Molecular Analysis of South African Ovine Herpesvirus 2 Strains Based on Selected Glycoprotein and Tegument Genes
por: Doboro, Fulufhelo Amanda, et al.
Publicado: (2016)

Immunization against a Conserved Surface Polysaccharide Stimulates Bovine Antibodies with Opsonic Killing Activity but Does Not Protect against Babesia bovis Challenge
por: Taus, Naomi S., et al.
Publicado: (2021)

An Evaluation of Quantitative PCR Assays (TaqMan(®) and SYBR Green) for the Detection of Babesia bigemina and Babesia bovis, and a Novel Fluorescent-ITS1-PCR Capillary Electrophoresis Method for Genotyping B. bovis Isolates
por: Zhang, Bing, et al.
Publicado: (2016)

Selection and evaluation of housekeeping genes as endogenous controls for quantification of mRNA transcripts in Theileria parva using quantitative real-time polymerase chain reaction (qPCR)
por: Tsotetsi, Teboho N., et al.
Publicado: (2018)

Identification of proteins expressed by Babesia bigemina kinetes
por: Bohaliga, Gamila A. R., et al.
Publicado: (2019)

The Structural Basis of Babesia orientalis Lactate Dehydrogenase
por: Yu, Long, et al.
Publicado: (2022)

Editorial: Exploring new technologies, investigating new targets, and shedding new light on Babesia
por: Gong, Haiyan, et al.
Publicado: (2022)

Molecular characterization and genetic diversity of Babesia bovis and Babesia bigemina of cattle in Thailand
por: Srionrod, Nitipon, et al.
Publicado: (2022)

Analysis of p67 allelic sequences reveals a subtype of allele type 1 unique to buffalo-derived Theileria parva parasites from southern Africa
por: Mukolwe, Lubembe D., et al.
Publicado: (2020)

N-Glycosylation in Piroplasmids: Diversity within Simplicity
por: Florin-Christensen, Monica, et al.
Publicado: (2021)

Stable transformation of Babesia bigemina and Babesia bovis using a single transfection plasmid
por: Silva, Marta G., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ouqe3i5v3ptb7krdcvfbdorkg1