Inactivation of the Pyrimidine Biosynthesis pyrD Gene Negatively Affects Biofilm Formation and Virulence Determinants in the Crohn’s Disease-Associated Adherent Invasive Escherichia coli LF82 Strain

In Crohn’s disease (CD) patients, the adherent-invasive Escherichia coli (AIEC) pathovar contributes to the chronic inflammation typical of the disease via its ability to invade gut epithelial cells and to survive in macrophages. We show that, in the AIEC strain LF82, inactivation of the pyrD gene,...

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Detalles Bibliográficos
Autores principales: Rossi, Elio, Leccese, Gabriella, Baldelli, Valerio, Bibi, Alessia, Scalone, Emanuele, Camilloni, Carlo, Paroni, Moira, Landini, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956108/
https://www.ncbi.nlm.nih.gov/pubmed/35336113
http://dx.doi.org/10.3390/microorganisms10030537

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