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PRP4KA phosphorylates SERRATE for degradation via 20S proteasome to fine-tune miRNA production in Arabidopsis

Phosphorylation can quickly switch on/off protein functions. Here, we reported pre-mRNA processing 4 kinase A (PRP4KA), and its paralogs interact with Serrate (SE), a key factor in RNA processing. PRP4KA phosphorylates at least five residues of SE in vitro and in vivo. Hypophosphorylated, but not hy...

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Detalles Bibliográficos
Autores principales:	Wang, Lin, Yan, Xingxing, Li, Yanjun, Wang, Zhiye, Chhajed, Shweta, Shang, Baoshuan, Wang, Zhen, Choi, Suk Won, Zhao, Hongwei, Chen, Sixue, Zhang, Xiuren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956257/ https://www.ncbi.nlm.nih.gov/pubmed/35333566 http://dx.doi.org/10.1126/sciadv.abm8435

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